Team CMMT in the BCCHF RBC Race for the Kids The annual BC Children’s Hospital Foundation Race for the Kids took place on Sunday, June 9th, 2024. A HUGE Congratulations to the 20 members of Team CMMT that helped fundraise a total of $3,363 for this important cause!
CMMT Summer Event – Baseball Game & Outdoor Social This June, the CMMT dusted off their baseball caps and headed to Nat Bailey Stadium for a ballgame followed by an outdoor social at Queen Elizabeth Park. Everyone had a “ball” of a time!!!
Publications Dylan V. Neel, M.Phill, Clara Baselga-Garriga, Molly Benson, Mackenzie Keegan, Marianne Chase, Derek D’Agostino, Kristin Drake, Jennifer Linn Hagar, Meredith Gibbons Hasenoehrl, Jennifer Kulesa-Kelley, Alex Leite, Silpa Mohapatra, Susanna Marie Portaro, Lindsay M. Pothier, Jesse Rosenthal, Alexander V. Sherman, Hong Yu, Alexandra McCaffrey1, Doreen Ho, Sarah Luppino, Richard Bedlack, Daragh Heitzman, MD, Senda Ajroud-Driss, Jonathan Katz, Kevin Felice, Charles Whitaker, Shafeeq Ladha, Gustavo Alameda, Eduardo Locatelli, MD, Irfan A. Qureshi, Michael T. Hotchkin, Michael R. Hayden, Merit E. Cudkowicz, Suma Babu, James D. Berry, Sabrina Paganoni. “Multi-center expanded access (EA) program for access to investigational products for amyotrophic lateral sclerosis (ALS).” Muscle and Nerve. PMID: 36929648 David J. Ecker, Clarice D. Aiello, Joseph R. Arron, C. Frank Bennett, Amy Bernard, Xandra O. Breakefield, Timothy J. Broderick, Shawneequa L. Callier, Barry Canton, Janice S. Chen, C. Simone Fishburn, Banning Garrett, Sidney Hecht, Tobias Janowitz, Melinda Kliegman, Adrian Krainer, Chrystal Louis, Christopher Lowe, Joni Rutter, Alfica Sehgal, Yesim Tozan, Kevin J. Tracey, Fyodor D. Urnov, Daniel Wattendorf, Thomas W. Williams, Xuanhe Zhao & Michael R. Hayden. Opportunities and challenges for innovative and equitable healthcare. Nature Drug Discovery. PMID: 38409339 van Karnebeek CDM, Tarailo-Graovac M, Leen R, Meinsma R, Correard S, Jansen-Meijer J, Prykhozhij SV, Pena IA, Ban K, Schock S, Saxena V, Pras-Raves ML, Drögemöller BI, Grootemaat AE, van der Wel NN, Dobritzsch D, Roseboom W, Schomakers BV, Jaspers YRJ, Zoetekouw L, Roelofsen J, Ferreira CR, van der Lee R, Ross CJ, Kochan J, McIntyre RL, van Klinken JB, van Weeghel M, Kramer G, Weschke B, Labrune P, Willemsen MA, Riva D, Garavaglia B, Moeschler JB, Filiano JJ, Ekker M, Berman JN, Dyment D, Vaz FM, Wasserman WW, Houtkooper RH, van Kuilenburg ABP, 2024, “CIAO1 and MMS19 deficiency: a lethal neurodegenerative phenotype caused by cytosolic Fe-S cluster protein assembly disorders”, Genetics in Medicine, 26, 101104. doi: https://doi.org/10.1016/j.gim.2024.101104. Li Z., Liang D., Ebelt S., Gearing M., Kobor M.S., Konwar C., Maclsaac J.L., Dever K., Wingo A.P., Levey A.I., Lah J.J., Wingo T.S., and Hüls A. (2024). Differential DNA Methylation in the Brain as Potential Mediator of the Association Between Traffic-related PM2.5 and Neuropathology Markers of Alzheimer’s Disease. Alzheimers Dement. 20:2538-2551. Eisenberg D.T.A., Ryan C.P., Lee N.R., Carba D.B., MacIsaac J.L., Dever K., Atashzay P., Kobor M.S., and Kuzawa C. (2024). DNA Methylation-based Estimators of Telomere Length Show Low Correspondence with Paternal Age at Conception and Other Measures of External Validity of Telomere Length. GeroScience. 10.1007/s11357-024-01114-2. Online ahead of print. Hastings W.J., Ye Q., Wolf S.E., Ryan C.P., Das S.K., Huffman K.M., Kobor M.S., Kraus W.E., MacIsaac J.L., Martin C.K., Racette S.B., Redman L.M., Belsky D.W., and Shalev I. (2024). Effect of Caloric Restriction on Telomere Length in Healthy Adults: CALERIE™ 2 Trial Analysis. Aging cell. e14149. Online ahead of print. Lee S., Sbihi H., MacIsaac J.L., Balshaw R., Ambalavanan A., Subbarao P., Mandhane P.J., Moraes T.J., Turvey S.E., Duan Q., Brauer M., Brook J.R., Kobor M.S., and Jones M.J. (2024). Persistent DNA Methylation Changes Across the First Year of Life and Prenatal NO2 Exposure in a Canadian Prospective Birth Study. Environ Health Perspect. 132: 47004. Ryan C.P., Lee N.R., Carba D.B., MacIsaac J.L., Lin D.T.S., Atashzay P., Belsky D.W., Kobor M.S., and Kuzawa C.W. (2024) Pregnancy is Linked to Faster Epigenetic Aging in Young Women. Proc Natl Acad Sci U S A. 121:e2317290121. Hernandez Cordero A.I., Li X., Xi Yang C., Ambalavanan A., MacIsaac J.L., Kobor M.S., Doiron D., Tan W., Bourbeau J., Sin D.D., Duan Q., and Leung J.M.; CanCOLD Collaborative Research Group. (2024) Cannabis Smoking is Associated with Advanced Epigenetic Age. Eur Respir J. 63:2400458. Pett L., Li Z., Abrishamcar S., Hodge K., Everson T., Christensen G., Gearing M., Kobor M.S., Konwar C., MacIsaac J.L., Dever K., Wingo A.P., Levey A., Lah J.J., Wingo T.S., and Hüls A. (2024) The Association Between Neighborhood Deprivation and DNA Methylation in an Autopsy Cohort. Aging. 16:6694-6716. Marchi E., Hinks T.S.C., Richardson M., Khalfaoui L., Symon F.A., Rajasekar P., Clifford R., Hargadon B., Austin C.D., MacIsaac J.L., Kobor M.S., Siddiqui S., Mar J.S., Arron J.R., Choy D.F., and Bradding P. (2024). The Effects of Inhaled Corticosteroids on Healthy Airways. Allergy. Doi: 10.1111/all.16146. Online ahead of print. Jiaming Xu, Brendil Sabatino, Junran Yan, Glafira Ermakova, Kelsie RS Doering, Stefan Taubert, S Lee. The unfolded protein response of the endoplasmic reticulum protects Caenorhabditis elegans against DNA damage caused by stalled replication forks. G3: Genes, Genomes, Genetics. 2024-04-03. DOI: 10.1093/g3journal/jkae017 Salama O.E., Hizon N., Del Vecchio M., Kolsun K., Fonseca M.A., Lin D.T.S., Urtatiz O., MacIsaac J.L., Kobor M.S., Sellers E.A.C., Dolinsky V.W., Dart A.B., Jones M.J., and Wicklow B.A. (2024). DNA Methylation Signatures of Youth-onset Type 2 Diabetes and Exposure to Maternal Diabetes. Clin Epigenetics. 16:65. Rada Tazhitdinova, Sara Cristiano, Joshua Yi, Valdimir Zhurov, Rodney P. De Koter, Alexander V. Timoshenko. Expression and secretion of galectin-12 in the context of neutrophilic differentiation of human promyeloblastic HL-60 cells. 30 April 2024. https://doi.org/10.1002/jcp.31288 |
Save The Date The annual CMMT Research Day will take place on September 27, 2024. Please join us for a day of trainee talks, faculty speakers, poster presentations, lunch, social and more!!!Guest Speaker: Kym M Boycott, Senior Scientist, CHEO Research Institute Faculty Speaker: Francesca Capon, Professor,Department of Medical Genetics, Senior Scientist, Centre for Molecular Medicine and Therapeutics (CMMT) Read more: https://cmmt.ubc.ca/2024/06/17/cmmt-research-day-september-27th-2024/ |
The annual Vancouver Gairdner National Symposium will take place on October 21, 2024. The two inspirational Gairdner Awardees speaking are:Dr. Michel Sadelain, MD, PhD: “For seminal contributions to the conception, development and application of CD19-CAR T cell therapy for cancer.’’Dr. David Klenerman, FRS, FMedSci: “For the fundamental and applied research that led to a revolutionary and affordable method to sequence DNA on a massive scale, which has dramatically accelerated discoveries in the life sciences and medicine. Read more: https://cmmt.ubc.ca/2024/06/07/save-the-date-2024-vancouver-gairdner-national-symposium-october-21-2024/ |
Special Announcements
Dr. Stefan Taubert has been promoted to the rank of Professor, with tenure, effective July 1, 2023
His commitment to teaching excellence, graduate supervision, research and community service contribute to advancing UBC’s vision as a global institution of learning and research.
Congratulations Stefan!
Read more about the Taubert Lab: https://cmmt.ubc.ca/taubert-lab/
Graduations Dr. Ben Life: PhD Thesis Title: Progranulin function and regulation in brain disease. Dr. Hilary Brewis: PhD Thesis Title: Deciphering H2A.Z-Mediated Transcriptional Regulation in Sacchromyces Cerevisiae. Dr. Zheng Dong: PhD Thesis Title: Investigating Evolutionary Conservation and Population Specificity of DNA Methylation. Rui Wang: MSc Thesis Title: Exploring the Impact of SNCA Overexpression on Mouse Hippocampal DNA Methylome and Transcriptome During Midlife. |
Awards and Scholarships Christine Chen, Dennis Lab CSG-M Award Ashleen Phandar, Hayden Lab HSC Undergraduate Summer Student Fellowship Award Dr. Neel Mehta, Hayden Lab BB&D Publication Fund https://pubmed.ncbi.nlm.nih.gov/37597209/ Meingold Chan, Kobor Lab CIHR Postdoctoral Fellowship Award Dr. Elizabeth Simpson, Simpson Lab 2024 Canucks for Kids Fund Diabetes Catalyst Grant competition https://www.bcchr.ca/diabetes Chiaki Shuzenji, Taubert Lab UBC Four Year Fellowship Dr. Stefan Taubert, Taubert Lab NSERC Discovery Grant Glafira Ermakova, Taubert Lab CIHR CGS-D Award James Wu, Taubert Lab UBC Healthy Aging Summer Student Research Award Rachel Spencer, Taubert Lab CIHR CGS-D Award Yuchang (Janice) Zhan, Taubert Lab UBC NSERC Undergraduate Student Research Award UBC Faculty of Medicine Summer Student Research Program (FoM SSRP) Award Dr. Wyeth Wasserman, Wasserman Lab NSERC Discovery Grant CIHR Project Grant (as co-applicant) Travel Award for the 2024-25 endMS Scholar Program for Researchers IN Training (SPRINT) Kiana Rashidi, Wasserman Lab BCCHRI Summer Studentship Work Learn International Undergraduate Research Award |
Fun Facts The deepest place on Earth is the Mariana Trench in the Pacific Ocean. The longest river in the world is the River Nile, clocking 6,853km in length. Did you know? Giraffes are 30 time more likely to get hit by lighting than people. There is a 50% chance that two people will share a birthday in a group of 23 people. |
Our next newsletter will be released September 2024. Submit storyline suggestions to media@cmmt.ubc.ca by August 15, 2024. Submit awards, events, publications, kudos, etc. to media@cmmt.ubc.ca by August 15, 2024. |
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