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Leadership Update: Bruce Verchere appointed Director, Centre for Molecular Medicine and Therapeutics

        Dear Colleagues, It is with great pleasure that we announce the appointment of Dr. Bruce Verchere as the Director of the Centre for Molecular Medicine and Therapeutics (CMMT).                 Dr. Verchere is a highly accomplished researcher and Professor in the Departments of Pathology and […]

2019 International Gairdner Symposium

The Gairdner International Symposium is held each fall to give students, teachers, and researchers the opportunity to hear from Gairdner award-winning scientists and attend a luncheon with the award winners. Watch the video of the 2019 Gairdner High School Symposium: HERE Watch the video of the 2019 Gairdner National Symposium: HERE Time: 3:30- 6:00 pm, Monday, October 21, 2019 […]

CMMT researchers mining 25 years of data uncovers a new predictor of age of onset for Huntington disease

May 16, 2019 Study lead author Galen Wright Investigators at the University of British Columbia (UBC) Centre for Molecular Medicine & Therapeutics (CMMT) and BC Children’s Hospital have examined more than 25 years of data to reveal new insights into predicting the age of onset for Huntington disease. “This discovery may enable us to provide […]

Huntington drug successfully lowers levels of disease-causing protein

An international clinical trial has found that a new drug for Huntington disease is safe, and that treatment with the drug successfully lowers levels of the abnormal protein that causes the debilitating disease in patients. In the study published today in the New England Journal of Medicine, researchers from UBC and their colleagues have demonstrated […]

Huntingtin Lowering Strategies for Disease Modification in Huntington’s Disease

Huntington’s disease is caused by an abnormally expanded CAG repeat expansion in the HTT gene, which confers a predominant toxic gain of function in the mutant huntingtin (mHTT) protein. There are currently no disease-modifying therapies available, but approaches that target proximally in disease pathogenesis hold great promise. These include DNA-targeting techniques such as zinc-finger proteins, transcription activator-like effector nucleases, […]

Trainee Spotlight: Jeffy Rajan

Kudos to Jeffy Rajan, recipient of a 2019 Brain, Behaviour and Development (BB&D) Trainee Boost Award.  Jeffy hangs out in the Goldowitz Lab and her project is “Impact of motor learning performance in Developmental Coordination Disorder (DCD)”. “I am very grateful to be the recipient of the BB&D Trainee Boost Award in recognition of a […]