Contact: ncaron@cmmt.ubc.ca
Cerebrospinal fluid (CSF) is an accessible biofluid whose molecular composition reflects structural and functional changes in the brain, making it a promising biofluid for biomarker discovery in neurodegenerative disorders. My primary research interests focus on the identification and validation of molecular biomarkers for Huntington disease, which offer the potential to monitor cell-type and/or pathway-specific pathophysiological alterations in the diseased brain. Such biomarkers may help improve predictions of Huntington disease onset, better define disease progression and could facilitate the evaluation of potential therapies.