Elizabeth Simpson Publications

  1. Baumann, BH, Shu, W, Song, Y, Simpson, EM, Lakhal-Littleton, S, Dunaief, JL et al.. Ferroportin-mediated iron export from vascular endothelial cells in retina and brain. Exp. Eye Res. 2019;187 :107728. doi: 10.1016/j.exer.2019.107728. PubMed PMID:31323276 PubMed Central PMC6759385.
  2. Peeters, SB, Korecki, AJ, Baldry, SEL, Yang, C, Tosefsky, K, Balaton, BP et al.. How do genes that escape from X-chromosome inactivation contribute to Turner syndrome?. Am J Med Genet C Semin Med Genet. 2019;181 (1):28-35. doi: 10.1002/ajmg.c.31672. PubMed PMID:30779428 .
  3. Korecki, AJ, Hickmott, JW, Lam, SL, Dreolini, L, Mathelier, A, Baker, O et al.. Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain, Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele. Genetics. 2019;211 (4):1155-1177. doi: 10.1534/genetics.119.301984. PubMed PMID:30765420 PubMed Central PMC6456315.
  4. Hickmott, JW, Gunawardane, U, Jensen, K, Korecki, AJ, Simpson, EM. Epistasis between Pax6Sey and genetic background reinforces the value of defined hybrid mouse models for therapeutic trials. Gene Ther. 2018;25 (8):524-537. doi: 10.1038/s41434-018-0043-6. PubMed PMID:30258099 PubMed Central PMC6335240.
  5. Simpson, EM, Korecki, AJ, Fornes, O, McGill, TJ, Cueva-Vargas, JL, Agostinone, J et al.. New MiniPromoter Ple345 (NEFL) Drives Strong and Specific Expression in Retinal Ganglion Cells of Mouse and Primate Retina. Hum. Gene Ther. 2019;30 (3):257-272. doi: 10.1089/hum.2018.118. PubMed PMID:30062914 PubMed Central PMC6437624.
  6. Peeters, SB, Korecki, AJ, Simpson, EM, Brown, CJ. Human cis-acting elements regulating escape from X-chromosome inactivation function in mouse. Hum. Mol. Genet. 2018;27 (7):1252-1262. doi: 10.1093/hmg/ddy039. PubMed PMID:29401310 PubMed Central PMC6159535.
  7. Connell, M, Chen, H, Jiang, J, Kuan, CW, Fotovati, A, Chu, TL et al.. HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development. Elife. 2017;6 :. doi: 10.7554/eLife.28672. PubMed PMID:28994651 PubMed Central PMC5681225.
  8. Corso-Díaz, X, de Leeuw, CN, Alonso, V, Melchers, D, Wong, BK, Houtman, R et al.. Co-activator candidate interactions for orphan nuclear receptor NR2E1. BMC Genomics. 2016;17 (1):832. doi: 10.1186/s12864-016-3173-5. PubMed PMID:27782803 PubMed Central PMC5080790.
  9. Hickmott, JW, Chen, CY, Arenillas, DJ, Korecki, AJ, Lam, SL, Molday, LL et al.. PAX6 MiniPromoters drive restricted expression from rAAV in the adult mouse retina. Mol Ther Methods Clin Dev. 2016;3 :16051. doi: 10.1038/mtm.2016.51. PubMed PMID:27556059 PubMed Central PMC4980111.
  10. de Leeuw, CN, Korecki, AJ, Berry, GE, Hickmott, JW, Lam, SL, Lengyell, TC et al.. rAAV-compatible MiniPromoters for restricted expression in the brain and eye. Mol Brain. 2016;9 (1):52. doi: 10.1186/s13041-016-0232-4. PubMed PMID:27164903 PubMed Central PMC4862195.
  11. Scalabrino, ML, Boye, SL, Fransen, KM, Noel, JM, Dyka, FM, Min, SH et al.. Intravitreal delivery of a novel AAV vector targets ON bipolar cells and restores visual function in a mouse model of complete congenital stationary night blindness. Hum. Mol. Genet. 2015;24 (21):6229-39. doi: 10.1093/hmg/ddv341. PubMed PMID:26310623 PubMed Central PMC4612567.
  12. Schmouth, JF, Arenillas, D, Corso-Díaz, X, Xie, YY, Bohacec, S, Banks, KG et al.. Combined serial analysis of gene expression and transcription factor binding site prediction identifies novel-candidate-target genes of Nr2e1 in neocortex development. BMC Genomics. 2015;16 :545. doi: 10.1186/s12864-015-1770-3. PubMed PMID:26204903 PubMed Central PMC4512088.
  13. Corso-Díaz, X, Simpson, EM. Nr2e1 regulates retinal lamination and the development of Müller glia, S-cones, and glycineric amacrine cells during retinogenesis. Mol Brain. 2015;8 :37. doi: 10.1186/s13041-015-0126-x. PubMed PMID:26092486 PubMed Central PMC4475312.
  14. de Leeuw, CN, Dyka, FM, Boye, SL, Laprise, S, Zhou, M, Chou, AY et al.. Targeted CNS Delivery Using Human MiniPromoters and Demonstrated Compatibility with Adeno-Associated Viral Vectors. Mol Ther Methods Clin Dev. 2014;1 :5. doi: 10.1038/mtm.2013.5. PubMed PMID:24761428 PubMed Central PMC3992516.
  15. Schmouth, JF, Castellarin, M, Laprise, S, Banks, KG, Bonaguro, RJ, McInerny, SC et al.. Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice. BMC Biol. 2013;11 :106. doi: 10.1186/1741-7007-11-106. PubMed PMID:24124870 PubMed Central PMC4015596.
  16. Corso-Díaz, X, Borrie, AE, Bonaguro, R, Schuetz, JM, Rosenberg, T, Jensen, H et al.. Absence of NR2E1 mutations in patients with aniridia. Mol. Vis. 2012;18 :2770-82. . PubMed PMID:23213277 PubMed Central PMC3513187.
  17. Yang, C, McLeod, AJ, Cotton, AM, de Leeuw, CN, Laprise, S, Banks, KG et al.. Targeting of >1.5 Mb of human DNA into the mouse X chromosome reveals presence of cis-acting regulators of epigenetic silencing. Genetics. 2012;192 (4):1281-93. doi: 10.1534/genetics.112.143743. PubMed PMID:23023002 PubMed Central PMC3512139.
  18. Bradley, A, Anastassiadis, K, Ayadi, A, Battey, JF, Bell, C, Birling, MC et al.. The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm. Genome. 2012;23 (9-10):580-6. doi: 10.1007/s00335-012-9422-2. PubMed PMID:22968824 PubMed Central PMC3463800.
  19. Murray, SA, Eppig, JT, Smedley, D, Simpson, EM, Rosenthal, N. Beyond knockouts: cre resources for conditional mutagenesis. Mamm. Genome. 2012;23 (9-10):587-99. doi: 10.1007/s00335-012-9430-2. PubMed PMID:22926223 PubMed Central PMC3655717.
  20. Yusuf, D, Butland, SL, Swanson, MI, Bolotin, E, Ticoll, A, Cheung, WA et al.. The transcription factor encyclopedia. Genome Biol. 2012;13 (3):R24. doi: 10.1186/gb-2012-13-3-r24. PubMed PMID:22458515 PubMed Central PMC3439975.
  21. Schmouth, JF, Bonaguro, RJ, Corso-Diaz, X, Simpson, EM. Modelling human regulatory variation in mouse: finding the function in genome-wide association studies and whole-genome sequencing. PLoS Genet. 2012;8 (3):e1002544. doi: 10.1371/journal.pgen.1002544. PubMed PMID:22396661 PubMed Central PMC3291530.
  22. Schmouth, JF, Banks, KG, Mathelier, A, Gregory-Evans, CY, Castellarin, M, Holt, RA et al.. Retina restored and brain abnormalities ameliorated by single-copy knock-in of human NR2E1 in null mice. Mol. Cell. Biol. 2012;32 (7):1296-311. doi: 10.1128/MCB.06016-11. PubMed PMID:22290436 PubMed Central PMC3302440.
  23. Aubrecht, J, Goad, ME, Czopik, AK, Lerner, CP, Johnson, KA, Simpson, EM et al.. A high G418-resistant neo(R) transgenic mouse and mouse embryonic fibroblast (MEF) feeder layers for cytotoxicity and gene targeting in vivo and in vitro. Drug Chem Toxicol. 2011;34 (4):433-9. doi: 10.3109/01480545.2010.544316. PubMed PMID:21740348 .
  24. Portales-Casamar, E, Swanson, DJ, Liu, L, de Leeuw, CN, Banks, KG, Ho Sui, SJ et al.. A regulatory toolbox of MiniPromoters to drive selective expression in the brain. Proc. Natl. Acad. Sci. U.S.A. 2010;107 (38):16589-94. doi: 10.1073/pnas.1009158107. PubMed PMID:20807748 PubMed Central PMC2944712.
  25. Wong, BK, Hossain, SM, Trinh, E, Ottmann, GA, Budaghzadeh, S, Zheng, QY et al.. Hyperactivity, startle reactivity and cell-proliferation deficits are resistant to chronic lithium treatment in adult Nr2e1(frc/frc) mice. Genes Brain Behav. 2010;9 (7):681-94. doi: 10.1111/j.1601-183X.2010.00602.x. PubMed PMID:20497236 PubMed Central PMC3292041.
  26. Milisavljevic, M, Hearty, T, Wong, TY, Portales-Casamar, E, Simpson, EM, Wasserman, WW et al.. Laboratory Animal Management Assistant (LAMA): a LIMS for active research colonies. Mamm. Genome. 2010;21 (5-6):224-30. doi: 10.1007/s00335-010-9258-6. PubMed PMID:20411264 PubMed Central PMC5047758.
  27. Mazarei, G, Neal, SJ, Becanovic, K, Luthi-Carter, R, Simpson, EM, Leavitt, BR et al.. Expression analysis of novel striatal-enriched genes in Huntington disease. Hum. Mol. Genet. 2010;19 (4):609-22. doi: 10.1093/hmg/ddp527. PubMed PMID:19934114 PubMed Central PMC2807369.
  28. Van Raamsdonk, CD, Bezrookove, V, Green, G, Bauer, J, Gaugler, L, O'Brien, JM et al.. Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. Nature. 2009;457 (7229):599-602. doi: 10.1038/nature07586. PubMed PMID:19078957 PubMed Central PMC2696133.
  29. Yang, GS, Banks, KG, Bonaguro, RJ, Wilson, G, Dreolini, L, de Leeuw, CN et al.. Next generation tools for high-throughput promoter and expression analysis employing single-copy knock-ins at the Hprt1 locus. Genomics. 2009;93 (3):196-204. doi: 10.1016/j.ygeno.2008.09.014. PubMed PMID:18950699 .
  30. D'Souza, CA, Chopra, V, Varhol, R, Xie, YY, Bohacec, S, Zhao, Y et al.. Identification of a set of genes showing regionally enriched expression in the mouse brain. BMC Neurosci. 2008;9 :66. doi: 10.1186/1471-2202-9-66. PubMed PMID:18625066 PubMed Central PMC2483290.
  31. Kumar, RA, McGhee, KA, Leach, S, Bonaguro, R, Maclean, A, Aguirre-Hernandez, R et al.. Initial association of NR2E1 with bipolar disorder and identification of candidate mutations in bipolar disorder, schizophrenia, and aggression through resequencing. Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008;147B (6):880-9. doi: 10.1002/ajmg.b.30696. PubMed PMID:18205168 .
  32. Kumar, RA, Everman, DB, Morgan, CT, Slavotinek, A, Schwartz, CE, Simpson, EM et al.. Absence of mutations in NR2E1 and SNX3 in five patients with MMEP (microcephaly, microphthalmia, ectrodactyly, and prognathism) and related phenotypes. BMC Med. Genet. 2007;8 :48. doi: 10.1186/1471-2350-8-48. PubMed PMID:17655765 PubMed Central PMC1950490.
  33. Oberlander, TF, Bonaguro, RJ, Misri, S, Papsdorf, M, Ross, CJ, Simpson, EM et al.. Infant serotonin transporter (SLC6A4) promoter genotype is associated with adverse neonatal outcomes after prenatal exposure to serotonin reuptake inhibitor medications. Mol. Psychiatry. 2008;13 (1):65-73. doi: 10.1038/sj.mp.4002007. PubMed PMID:17519929 .
  34. Kumar, RA, Leach, S, Bonaguro, R, Chen, J, Yokom, DW, Abrahams, BS et al.. Mutation and evolutionary analyses identify NR2E1-candidate-regulatory mutations in humans with severe cortical malformations. Genes Brain Behav. 2007;6 (6):503-16. doi: 10.1111/j.1601-183X.2006.00277.x. PubMed PMID:17054721 PubMed Central PMC2040186.
  35. Houde, C, Dickinson, RJ, Houtzager, VM, Cullum, R, Montpetit, R, Metzler, M et al.. Hippi is essential for node cilia assembly and Sonic hedgehog signaling. Dev. Biol. 2006;300 (2):523-33. doi: 10.1016/j.ydbio.2006.09.001. PubMed PMID:17027958 PubMed Central PMC5053816.
  36. Devon, RS, Orban, PC, Gerrow, K, Barbieri, MA, Schwab, C, Cao, LP et al.. Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities. Proc. Natl. Acad. Sci. U.S.A. 2006;103 (25):9595-600. doi: 10.1073/pnas.0510197103. PubMed PMID:16769894 PubMed Central PMC1480452.
  37. Kuo, BY, Chen, Y, Bohacec, S, Johansson, O, Wasserman, WW, Simpson, EM et al.. SAGE2Splice: unmapped SAGE tags reveal novel splice junctions. PLoS Comput. Biol. 2006;2 (4):e34. doi: 10.1371/journal.pcbi.0020034. PubMed PMID:16683015 PubMed Central PMC1447652.
  38. Siddiqui, AS, Khattra, J, Delaney, AD, Zhao, Y, Astell, C, Asano, J et al.. A mouse atlas of gene expression: large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells. Proc. Natl. Acad. Sci. U.S.A. 2005;102 (51):18485-90. doi: 10.1073/pnas.0509455102. PubMed PMID:16352711 PubMed Central PMC1311911.
  39. Christie, BR, Li, AM, Redila, VA, Booth, H, Wong, BK, Eadie, BD et al.. Deletion of the nuclear receptor Nr2e1 impairs synaptic plasticity and dendritic structure in the mouse dentate gyrus. Neuroscience. 2006;137 (3):1031-7. doi: 10.1016/j.neuroscience.2005.08.091. PubMed PMID:16289828 .
  40. Abrahams, BS, Kwok, MC, Trinh, E, Budaghzadeh, S, Hossain, SM, Simpson, EM et al.. Pathological aggression in "fierce" mice corrected by human nuclear receptor 2E1. J. Neurosci. 2005;25 (27):6263-70. doi: 10.1523/JNEUROSCI.4757-04.2005. PubMed PMID:16000615 PubMed Central PMC6725287.
  41. Janssen, PA, Nicholls, TL, Kumar, RA, Stefanakis, H, Spidel, AL, Simpson, EM et al.. Of mice and men: will the intersection of social science and genetics create new approaches for intimate partner violence?. J Interpers Violence. 2005;20 (1):61-71. doi: 10.1177/0886260504268120. PubMed PMID:15618562 .
  42. Houde, C, Banks, KG, Coulombe, N, Rasper, D, Grimm, E, Roy, S et al.. Caspase-7 expanded function and intrinsic expression level underlies strain-specific brain phenotype of caspase-3-null mice. J. Neurosci. 2004;24 (44):9977-84. doi: 10.1523/JNEUROSCI.3356-04.2004. PubMed PMID:15525783 PubMed Central PMC6730247.
  43. Fedele, DE, Koch, P, Scheurer, L, Simpson, EM, Möhler, H, Brüstle, O et al.. Engineering embryonic stem cell derived glia for adenosine delivery. Neurosci. Lett. 2004;370 (2-3):160-5. doi: 10.1016/j.neulet.2004.08.031. PubMed PMID:15488315 .
  44. Hossain, SM, Wong, BK, Simpson, EM. The dark phase improves genetic discrimination for some high throughput mouse behavioral phenotyping. Genes Brain Behav. 2004;3 (3):167-77. doi: 10.1111/j.1601-183x.2004.00069.x. PubMed PMID:15140012 .
  45. Kumar, RA, Chan, KL, Wong, AH, Little, KQ, Rajcan-Separovic, E, Abrahams, BS et al.. Unexpected embryonic stem (ES) cell mutations represent a concern in gene targeting: lessons from "fierce" mice. Genesis. 2004;38 (2):51-7. doi: 10.1002/gene.20001. PubMed PMID:14994267 .
  46. Banks, KG, Johnson, KA, Lerner, CP, Mahaffey, CL, Bronson, RT, Simpson, EM et al.. Retroposon compensatory mechanism hypothesis not supported: Zfa knockout mice are fertile. Genomics. 2003;82 (3):254-60. doi: 10.1016/s0888-7543(03)00155-1. PubMed PMID:12906850 .
  47. Abrahams, BS, Chong, AC, Nisha, M, Milette, D, Brewster, DA, Berry, ML et al.. Metaphase FISHing of transgenic mice recommended: FISH and SKY define BAC-mediated balanced translocation. Genesis. 2003;36 (3):134-41. doi: 10.1002/gene.10205. PubMed PMID:12872244 .
  48. Slow, EJ, van Raamsdonk, J, Rogers, D, Coleman, SH, Graham, RK, Deng, Y et al.. Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease. Hum. Mol. Genet. 2003;12 (13):1555-67. doi: 10.1093/hmg/ddg169. PubMed PMID:12812983 .
  49. Simpson, EM, Johnson, KA, Shirley, BJ, Fang, GY, Bayleran, JK, Lerner, CP et al.. Novel Sxr(a) ES cell line offers hope for Y chromosome gene-targeted mice. Genesis. 2002;33 (2):62-6. doi: 10.1002/gene.10093. PubMed PMID:12112873 .
  50. Abrahams, BS, Mak, GM, Berry, ML, Palmquist, DL, Saionz, JR, Tay, A et al.. Novel vertebrate genes and putative regulatory elements identified at kidney disease and NR2E1/fierce loci. Genomics. 2002;80 (1):45-53. doi: 10.1006/geno.2002.6795. PubMed PMID:12079282 .
  51. Young, KA, Berry, ML, Mahaffey, CL, Saionz, JR, Hawes, NL, Chang, B et al.. Fierce: a new mouse deletion of Nr2e1; violent behaviour and ocular abnormalities are background-dependent. Behav. Brain Res. 2002;132 (2):145-58. doi: 10.1016/s0166-4328(01)00413-2. PubMed PMID:11997145 PubMed Central PMC2862907.
  52. Collins, EC, Pannell, R, Simpson, EM, Forster, A, Rabbitts, TH. Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development. EMBO Rep. 2000;1 (2):127-32. doi: 10.1093/embo-reports/kvd021. PubMed PMID:11265751 PubMed Central PMC1084253.
  53. Linnell, ER, Lerner, CP, Johnson, KA, Leach, CA, Ulrich, TR, Rafferty, WC et al.. Transgenic mice for the preparation of puromycin-resistant primary embryonic fibroblast feeder layers for embryonic stem cell selection. Mamm. Genome. 2001;12 (2):169-71. doi: 10.1007/s003350010238. PubMed PMID:11210188 .
  54. Festing, MF, Simpson, EM, Davisson, MT, Mobraaten, LE. Revised nomenclature for strain 129 mice. Mamm. Genome. 1999;10 (8):836. doi: 10.1007/s003359901099. PubMed PMID:10430671 .
  55. Bergstrom, DE, Grieco, DA, Sonti, MM, Fawcett, JJ, Bell-Prince, C, Cram, LS et al.. The mouse Y chromosome: enrichment, sizing, and cloning by bivariate flow cytometry. Genomics. 1998;48 (3):304-13. doi: 10.1006/geno.1997.5176. PubMed PMID:9545635 .
  56. George, JF, Sweeney, SD, Kirklin, JK, Simpson, EM, Goldstein, DR, Thomas, JM et al.. An essential role for Fas ligand in transplantation tolerance induced by donor bone marrow. Nat. Med. 1998;4 (3):333-5. doi: 10.1038/nm0398-333. PubMed PMID:9500608 .
  57. Anon. Mutant mice and neuroscience: recommendations concerning genetic background. Banbury Conference on genetic background in mice. Neuron. 1997;19 (4):755-9. doi: 10.1016/s0896-6273(00)80958-7. PubMed PMID:9354323 .
  58. Bergstrom, DE, Yan, H, Sonti, MM, Narayanswami, S, Bayleran, JK, Simpson, EM et al.. An expanded collection of mouse Y chromosome RDA clones. Mamm. Genome. 1997;8 (7):510-2. doi: 10.1007/s003359900486. PubMed PMID:9195997 PubMed Central PMC2700750.
  59. Mbikay, M, Tadros, H, Ishida, N, Lerner, CP, De Lamirande, E, Chen, A et al.. Impaired fertility in mice deficient for the testicular germ-cell protease PC4. Proc. Natl. Acad. Sci. U.S.A. 1997;94 (13):6842-6. doi: 10.1073/pnas.94.13.6842. PubMed PMID:9192653 PubMed Central PMC21246.
  60. Aubrecht, J, Goad, ME, Simpson, EM, Schiestl, RH. Expression of hygR in transgenic mice causes resistance to toxic effects of hygromycin B in vivo. J. Pharmacol. Exp. Ther. 1997;281 (2):992-7. . PubMed PMID:9152410 .
  61. Simpson, EM, Linder, CC, Sargent, EE, Davisson, MT, Mobraaten, LE, Sharp, JJ et al.. Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice. Nat. Genet. 1997;16 (1):19-27. doi: 10.1038/ng0597-19. PubMed PMID:9140391 .
  62. Enerbäck, S, Jacobsson, A, Simpson, EM, Guerra, C, Yamashita, H, Harper, ME et al.. Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese. Nature. 1997;387 (6628):90-4. doi: 10.1038/387090a0. PubMed PMID:9139827 .
  63. Mahaffey, CL, Bayleran, JK, Yeh, GY, Lee, TC, Page, DC, Simpson, EM et al.. Intron/exon structure confirms that mouse Zfy1 and Zfy2 are members of the ZFY gene family. Genomics. 1997;41 (1):123-7. doi: 10.1006/geno.1997.4611. PubMed PMID:9126493 .
  64. Borriello, F, Sethna, MP, Boyd, SD, Schweitzer, AN, Tivol, EA, Jacoby, D et al.. B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation. Immunity. 1997;6 (3):303-13. doi: 10.1016/s1074-7613(00)80333-7. PubMed PMID:9075931 .
  65. Navin, A, Prekeris, R, Lisitsyn, NA, Sonti, MM, Grieco, DA, Narayanswami, S et al.. Mouse Y-specific repeats isolated by whole chromosome representational difference analysis. Genomics. 1996;36 (2):349-53. doi: 10.1006/geno.1996.0473. PubMed PMID:8812464 .
  66. Bayleran, JK, Yan, H, Hopper, CA, Simpson, EM. Frequencies of cystic fibrosis mutations in the Maine population: high proportion of unknown alleles in individuals of French-Canadian ancestry. Hum. Genet. 1996;98 (2):207-9. doi: 10.1007/s004390050192. PubMed PMID:8698344 .
  67. Mbikay, M, Tadros, H, Seidah, NG, Simpson, EM. Linkage mapping of the gene for the LIM-homeoprotein LIM3 (locus Lhx3) to mouse chromosome 2. Mamm. Genome. 1995;6 (11):818-9. doi: 10.1007/bf00539012. PubMed PMID:8597642 .
  68. Johnson, KA, Lerner, CP, Di Lacio, LC, Laird, PW, Sharpe, AH, Simpson, EM et al.. Transgenic mice for the preparation of hygromycin-resistant primary embryonic fibroblast feeder layers for embryonic stem cell selections. Nucleic Acids Res. 1995;23 (7):1273-5. doi: 10.1093/nar/23.7.1273. PubMed PMID:7739908 PubMed Central PMC306843.
  69. Mbikay, M, Seidah, NG, Chrétien, M, Simpson, EM. Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human. Genomics. 1995;26 (1):123-9. doi: 10.1016/0888-7543(95)80090-9. PubMed PMID:7782070 .
  70. Zambrowicz, BP, Findley, SD, Simpson, EM, Page, DC, Palmiter, RD. Characterization of the murine Zfy1 and Zfy2 promoters. Genomics. 1994;24 (2):406-8. doi: 10.1006/geno.1994.1641. PubMed PMID:7698773 .
  71. Zambrowicz, BP, Zimmermann, JW, Harendza, CJ, Simpson, EM, Page, DC, Brinster, RL et al.. Expression of a mouse Zfy-1/lacZ transgene in the somatic cells of the embryonic gonad and germ cells of the adult testis. Development. 1994;120 (6):1549-59. . PubMed PMID:8050362 .
  72. Simpson, EM, Page, DC. An interstitial deletion in mouse Y chromosomal DNA created a transcribed Zfy fusion gene. Genomics. 1991;11 (3):601-8. doi: 10.1016/0888-7543(91)90067-o. PubMed PMID:1774064 .
  73. Page, DC, Disteche, CM, Simpson, EM, de la Chapelle, A, Andersson, M, Alitalo, T et al.. Chromosomal localization of ZFX--a human gene that escapes X inactivation--and its murine homologs. Genomics. 1990;7 (1):37-46. doi: 10.1016/0888-7543(90)90516-w. PubMed PMID:1970799 .
  74. Mardon, G, Luoh, SW, Simpson, EM, Gill, G, Brown, LG, Page, DC et al.. Mouse Zfx protein is similar to Zfy-2: each contains an acidic activating domain and 13 zinc fingers. Mol. Cell. Biol. 1990;10 (2):681-8. doi: 10.1128/mcb.10.2.681. PubMed PMID:2105457 PubMed Central PMC360866.
  75. Page, DC, Mosher, R, Simpson, EM, Fisher, EM, Mardon, G, Pollack, J et al.. The sex-determining region of the human Y chromosome encodes a finger protein. Cell. 1987;51 (6):1091-104. doi: 10.1016/0092-8674(87)90595-2. PubMed PMID:3690661 .
  76. Himmelfarb, HJ, Simpson, EM, Friesen, JD. Isolation and characterization of temperature-sensitive RNA polymerase II mutants of Saccharomyces cerevisiae. Mol. Cell. Biol. 1987;7 (6):2155-64. doi: 10.1128/mcb.7.6.2155. PubMed PMID:3299061 PubMed Central PMC365338.
  77. Elliott, EM, Henderson, G, Sarangi, F, Ling, V. Complete sequence of three alpha-tubulin cDNAs in Chinese hamster ovary cells: each encodes a distinct alpha-tubulin isoprotein. Mol. Cell. Biol. 1986;6 (3):906-13. doi: 10.1128/mcb.6.3.906. PubMed PMID:3773896 PubMed Central PMC367591.
  78. Elliott, EM, Sarangi, F, Henderson, G, Ling, V. Cloning of 11 alpha-tubulin gene sequences from the genome of Chinese hamster ovary cells. Can. J. Biochem. Cell Biol. 1985;63 (6):511-8. doi: 10.1139/o85-070. PubMed PMID:2931165 .
  79. Elliott, EM, Okayama, H, Sarangi, F, Henderson, G, Ling, V. Differential expression of three alpha-tubulin genes in Chinese hamster ovary cells. Mol. Cell. Biol. 1985;5 (1):236-41. doi: 10.1128/mcb.5.1.236. PubMed PMID:3982416 PubMed Central PMC366698.
  80. Elliott, EM, Ling, V. Selection and characterization of Chinese hamster ovary cell mutants resistant to melphalan (L-phenylalanine mustard). Cancer Res. 1981;41 (2):393-400. . PubMed PMID:7448783 .
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