- Korecki, AJ, Hickmott, JW, Lam, SL, Dreolini, L, Mathelier, A, Baker, O et al.. Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain; Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele. Genetics. 2019; :. doi: 10.1534/genetics.119.301984. PubMed PMID:30765420 .
- Ranger, M, Tremblay, S, Chau, CMY, Holsti, L, Grunau, RE, Goldowitz, D et al.. Adverse Behavioral Changes in Adult Mice Following Neonatal Repeated Exposure to Pain and Sucrose. Front Psychol. 2018;9 :2394. doi: 10.3389/fpsyg.2018.02394. PubMed PMID:30719013 PubMed Central PMC6348336.
- Théberge, ET, Baker, JA, Dubose, C, Boyle, JK, Balce, K, Goldowitz, D et al.. Genetic Influences on the Amount of Cell Death in the Neural Tube of BXD Mice Exposed to Acute Ethanol at Midgestation. Alcohol. Clin. Exp. Res. 2018; :. doi: 10.1111/acer.13947. PubMed PMID:30589433 .
- Zhang, P, Dimont, E, Ha, T, Swanson, DJ, Itoh, M, Kawaji, H et al.. Correction to: Relatively frequent switching of transcription start sites during cerebellar development. BMC Genomics. 2018;19 (1):39. doi: 10.1186/s12864-017-4291-4. PubMed PMID:29325522 PubMed Central PMC5763542.
- Zhang, PGY, Yeung, J, Gupta, I, Ramirez, M, Ha, T, Swanson, DJ et al.. Discovery of Transcription Factors Novel to Mouse Cerebellar Granule Cell Development Through Laser-Capture Microdissection. Cerebellum. 2018;17 (3):308-325. doi: 10.1007/s12311-017-0912-3. PubMed PMID:29307116 .
- Connell, M, Chen, H, Jiang, J, Kuan, CW, Fotovati, A, Chu, TL et al.. HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development. Elife. 2017;6 :. doi: 10.7554/eLife.28672. PubMed PMID:28994651 PubMed Central PMC5681225.
- Roy, S, Yun, D, Madahian, B, Berry, MW, Deng, LY, Goldowitz, D et al.. Navigating the Functional Landscape of Transcription Factors via Non-Negative Tensor Factorization Analysis of MEDLINE Abstracts. Front Bioeng Biotechnol. 2017;5 :48. doi: 10.3389/fbioe.2017.00048. PubMed PMID:28894735 PubMed Central PMC5581332.
- Noguchi, S, Arakawa, T, Fukuda, S, Furuno, M, Hasegawa, A, Hori, F et al.. FANTOM5 CAGE profiles of human and mouse samples. Sci Data. 2017;4 :170112. doi: 10.1038/sdata.2017.112. PubMed PMID:28850106 PubMed Central PMC5574368.
- de Rie, D, Abugessaisa, I, Alam, T, Arner, E, Arner, P, Ashoor, H et al.. An integrated expression atlas of miRNAs and their promoters in human and mouse. Nat. Biotechnol. 2017;35 (9):872-878. doi: 10.1038/nbt.3947. PubMed PMID:28829439 PubMed Central PMC5767576.
- Tremblay, S, Pai, A, Richter, L, Vafaei, R, Potluri, P, Ellegood, J et al.. Systemic inflammation combined with neonatal cerebellar haemorrhage aggravates long-term structural and functional outcomes in a mouse model. Brain Behav. Immun. 2017;66 :257-276. doi: 10.1016/j.bbi.2017.07.013. PubMed PMID:28755859 .
- Tremblay, S, Ranger, M, Chau, CMY, Ellegood, J, Lerch, JP, Holsti, L et al.. Repeated exposure to sucrose for procedural pain in mouse pups leads to long-term widespread brain alterations. Pain. 2017;158 (8):1586-1598. doi: 10.1097/j.pain.0000000000000961. PubMed PMID:28715355 PubMed Central PMC5539923.
- Zhang, P, Dimont, E, Ha, T, Swanson, DJ, FANTOM Consortium, Hide, W et al.. Relatively frequent switching of transcription start sites during cerebellar development. BMC Genomics. 2017;18 (1):461. doi: 10.1186/s12864-017-3834-z. PubMed PMID:28610618 PubMed Central PMC5470264.
- Yeung, J, Goldowitz, D. Wls expression in the rhombic lip orchestrates the embryonic development of the mouse cerebellum. Neuroscience. 2017;354 :30-42. doi: 10.1016/j.neuroscience.2017.04.020. PubMed PMID:28450263 .
- Yeung, J, Ha, TJ, Swanson, DJ, Goldowitz, D. A Novel and Multivalent Role of Pax6 in Cerebellar Development. J. Neurosci. 2016;36 (35):9057-69. doi: 10.1523/JNEUROSCI.4385-15.2016. PubMed PMID:27581449 PubMed Central PMC5005719.
- Calton, MA, Howard, JR, Harper, RM, Goldowitz, D, Mittleman, G. The Cerebellum and SIDS: Disordered Breathing in a Mouse Model of Developmental Cerebellar Purkinje Cell Loss during Recovery from Hypercarbia. Front Neurol. 2016;7 :78. doi: 10.3389/fneur.2016.00078. PubMed PMID:27242661 PubMed Central PMC4865515.
- de Leeuw, CN, Korecki, AJ, Berry, GE, Hickmott, JW, Lam, SL, Lengyell, TC et al.. rAAV-compatible MiniPromoters for restricted expression in the brain and eye. Mol Brain. 2016;9 (1):52. doi: 10.1186/s13041-016-0232-4. PubMed PMID:27164903 PubMed Central PMC4862195.
- Dickson, PE, Cairns, J, Goldowitz, D, Mittleman, G. Cerebellar contribution to higher and lower order rule learning and cognitive flexibility in mice. Neuroscience. 2017;345 :99-109. doi: 10.1016/j.neuroscience.2016.03.040. PubMed PMID:27012612 PubMed Central PMC5031514.
- Cairns, J, Swanson, D, Yeung, J, Sinova, A, Chan, R, Potluri, P et al.. Abnormalities in the Structure and Function of Cerebellar Neurons and Neuroglia in the Lc/+ Chimeric Mouse Model of Variable Developmental Purkinje Cell Loss. Cerebellum. 2017;16 (1):40-54. doi: 10.1007/s12311-015-0756-7. PubMed PMID:26837618 .
- Dickson, PE, Miller, MM, Calton, MA, Bubier, JA, Cook, MN, Goldowitz, D et al.. Systems genetics of intravenous cocaine self-administration in the BXD recombinant inbred mouse panel. Psychopharmacology (Berl.). 2016;233 (4):701-14. doi: 10.1007/s00213-015-4147-z. PubMed PMID:26581503 PubMed Central PMC4803082.
- Zhang, P, Ha, T, Larouche, M, Swanson, D, Goldowitz, D. Kruppel-Like Factor 4 Regulates Granule Cell Pax6 Expression and Cell Proliferation in Early Cerebellar Development. PLoS ONE. 2015;10 (7):e0134390. doi: 10.1371/journal.pone.0134390. PubMed PMID:26226504 PubMed Central PMC4520560.
- Arner, E, Daub, CO, Vitting-Seerup, K, Andersson, R, Lilje, B, Drabløs, F et al.. Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells. Science. 2015;347 (6225):1010-4. doi: 10.1126/science.1259418. PubMed PMID:25678556 PubMed Central PMC4681433.
- Vitezic, M, Bertin, N, Andersson, R, Lipovich, L, Kawaji, H, Lassmann, T et al.. CAGE-defined promoter regions of the genes implicated in Rett Syndrome. BMC Genomics. 2014;15 :1177. doi: 10.1186/1471-2164-15-1177. PubMed PMID:25539566 PubMed Central PMC4522966.
- Ha, T, Swanson, D, Larouche, M, Glenn, R, Weeden, D, Zhang, P et al.. CbGRiTS: cerebellar gene regulation in time and space. Dev. Biol. 2015;397 (1):18-30. doi: 10.1016/j.ydbio.2014.09.032. PubMed PMID:25446528 .
- Yeung, J, Ha, TJ, Swanson, DJ, Choi, K, Tong, Y, Goldowitz, D et al.. Wls provides a new compartmental view of the rhombic lip in mouse cerebellar development. J. Neurosci. 2014;34 (37):12527-37. doi: 10.1523/JNEUROSCI.1330-14.2014. PubMed PMID:25209290 PubMed Central PMC4160781.
- Calton, M, Dickson, P, Harper, RM, Goldowitz, D, Mittleman, G. Impaired hypercarbic and hypoxic responses from developmental loss of cerebellar Purkinje neurons: implications for sudden infant death syndrome. Cerebellum. 2014;13 (6):739-50. doi: 10.1007/s12311-014-0592-1. PubMed PMID:25132500 PubMed Central PMC4462133.
- Goldowitz, D, Lussier, AA, Boyle, JK, Wong, K, Lattimer, SL, Dubose, C et al.. Molecular pathways underpinning ethanol-induced neurodegeneration. Front Genet. 2014;5 :203. doi: 10.3389/fgene.2014.00203. PubMed PMID:25076964 PubMed Central PMC4097813.
- de Leeuw, CN, Dyka, FM, Boye, SL, Laprise, S, Zhou, M, Chou, AY et al.. Targeted CNS Delivery Using Human MiniPromoters and Demonstrated Compatibility with Adeno-Associated Viral Vectors. Mol Ther Methods Clin Dev. 2014;1 :5. doi: 10.1038/mtm.2013.5. PubMed PMID:24761428 PubMed Central PMC3992516.
- FANTOM Consortium and the RIKEN PMI and CLST (DGT), Forrest, AR, Kawaji, H, Rehli, M, Baillie, JK, de Hoon, MJ et al.. A promoter-level mammalian expression atlas. Nature. 2014;507 (7493):462-70. doi: 10.1038/nature13182. PubMed PMID:24670764 PubMed Central PMC4529748.
- Poon, A, Goldowitz, D. Identification of genetic loci that modulate cell proliferation in the adult rostral migratory stream using the expanded panel of BXD mice. BMC Genomics. 2014;15 :206. doi: 10.1186/1471-2164-15-206. PubMed PMID:24640950 PubMed Central PMC4004255.
- Mary-Sinclair, MN, Wang, X, Swanson, DJ, Sung, CY, Mendonca, EA, Wroblewski, K et al.. Varied manifestations of persistent hyperplastic primary vitreous with graded somatic mosaic deletion of a single gene. Mol. Vis. 2014;20 :215-30. . PubMed PMID:24623965 PubMed Central PMC3945809.
- Balsevich, G, Poon, A, Goldowitz, D, Wilking, JA. The effects of pre- and post-natal nicotine exposure and genetic background on the striatum and behavioral phenotypes in the mouse. Behav. Brain Res. 2014;266 :7-18. doi: 10.1016/j.bbr.2014.02.038. PubMed PMID:24607511 .
- Racine, E, Bell, E, Yan, A, Andrew, G, Bell, LE, Clarke, M et al.. Ethics challenges of transition from paediatric to adult health care services for young adults with neurodevelopmental disabilities. Paediatr Child Health. 2014;19 (2):65-8. . PubMed PMID:24596475 PubMed Central PMC3941669.
- McKimm, E, Corkill, B, Goldowitz, D, Albritton, LM, Homayouni, R, Blaha, CD et al.. Glutamate dysfunction associated with developmental cerebellar damage: relevance to autism spectrum disorders. Cerebellum. 2014;13 (3):346-53. doi: 10.1007/s12311-013-0541-4. PubMed PMID:24307139 PubMed Central PMC4060592.
- Yoo, JY, Mak, GK, Goldowitz, D. The effect of hemorrhage on the development of the postnatal mouse cerebellum. Exp. Neurol. 2014;252 :85-94. doi: 10.1016/j.expneurol.2013.11.010. PubMed PMID:24252180 .
- Schmouth, JF, Castellarin, M, Laprise, S, Banks, KG, Bonaguro, RJ, McInerny, SC et al.. Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice. BMC Biol. 2013;11 :106. doi: 10.1186/1741-7007-11-106. PubMed PMID:24124870 PubMed Central PMC4015596.
- Goldowitz, D. Excessive activation of tissue plasminogen activator makes a mouse nervous. Proc. Natl. Acad. Sci. U.S.A. 2013;110 (27):10882-3. doi: 10.1073/pnas.1309965110. PubMed PMID:23792578 PubMed Central PMC3704036.
- Dickson, PE, Corkill, B, McKimm, E, Miller, MM, Calton, MA, Goldowitz, D et al.. Effects of stimulus salience on touchscreen serial reversal learning in a mouse model of fragile X syndrome. Behav. Brain Res. 2013;252 :126-35. doi: 10.1016/j.bbr.2013.05.060. PubMed PMID:23747611 PubMed Central PMC3854797.
- Rogers, TD, McKimm, E, Dickson, PE, Goldowitz, D, Blaha, CD, Mittleman, G et al.. Is autism a disease of the cerebellum? An integration of clinical and pre-clinical research. Front Syst Neurosci. 2013;7 :15. doi: 10.3389/fnsys.2013.00015. PubMed PMID:23717269 PubMed Central PMC3650713.
- Rogers, TD, Dickson, PE, McKimm, E, Heck, DH, Goldowitz, D, Blaha, CD et al.. Reorganization of circuits underlying cerebellar modulation of prefrontal cortical dopamine in mouse models of autism spectrum disorder. Cerebellum. 2013;12 (4):547-56. doi: 10.1007/s12311-013-0462-2. PubMed PMID:23436049 PubMed Central PMC3854915.
- Yoo, JY, Larouche, M, Goldowitz, D. The expression of HDAC1 and HDAC2 during cerebellar cortical development. Cerebellum. 2013;12 (4):534-46. doi: 10.1007/s12311-013-0459-x. PubMed PMID:23436026 .
- Poon, A, Goldowitz, D. Effects of age and strain on cell proliferation in the mouse rostral migratory stream. Neurobiol. Aging. 2013;34 (6):1712.e15-21. doi: 10.1016/j.neurobiolaging.2012.12.021. PubMed PMID:23369547 .
- Qiao, S, Kim, SH, Heck, D, Goldowitz, D, LeDoux, MS, Homayouni, R et al.. Dab2IP GTPase activating protein regulates dendrite development and synapse number in cerebellum. PLoS ONE. 2013;8 (1):e53635. doi: 10.1371/journal.pone.0053635. PubMed PMID:23326475 PubMed Central PMC3541190.
- DuBose, CS, Chesler, EJ, Goldowitz, D, Hamre, KM. Use of the expanded panel of BXD mice narrow QTL regions in ethanol-induced locomotor activation and motor incoordination. Alcohol. Clin. Exp. Res. 2013;37 (1):170-83. doi: 10.1111/j.1530-0277.2012.01865.x. PubMed PMID:23289978 .
- Liu, L, Hamre, KM, Goldowitz, D. Kainic acid-induced neuronal degeneration in hippocampal pyramidal neurons is driven by both intrinsic and extrinsic factors: analysis of FVB/N↔C57BL/6 chimeras. J. Neurosci. 2012;32 (35):12093-101. doi: 10.1523/JNEUROSCI.6478-11.2012. PubMed PMID:22933793 .
- Ha, TJ, Swanson, DJ, Kirova, R, Yeung, J, Choi, K, Tong, Y et al.. Genome-wide microarray comparison reveals downstream genes of Pax6 in the developing mouse cerebellum. Eur. J. Neurosci. 2012;36 (7):2888-98. doi: 10.1111/j.1460-9568.2012.08221.x. PubMed PMID:22817342 PubMed Central PMC4189819.
- Fatemi, SH, Aldinger, KA, Ashwood, P, Bauman, ML, Blaha, CD, Blatt, GJ et al.. Consensus paper: pathological role of the cerebellum in autism. Cerebellum. 2012;11 (3):777-807. doi: 10.1007/s12311-012-0355-9. PubMed PMID:22370873 PubMed Central PMC3677555.
- Goldowitz, D. Linking early brain and biological development to psychiatry. J Can Acad Child Adolesc Psychiatry. 2011;20 (4):252. . PubMed PMID:22114606 PubMed Central PMC3222568.
- Tong, Y, Ha, TJ, Liu, L, Nishimoto, A, Reiner, A, Goldowitz, D et al.. Spatial and temporal requirements for huntingtin (Htt) in neuronal migration and survival during brain development. J. Neurosci. 2011;31 (41):14794-9. doi: 10.1523/JNEUROSCI.2774-11.2011. PubMed PMID:21994396 PubMed Central PMC3407803.
- Ouyang, Z, Song, M, Güth, R, Ha, TJ, Larouche, M, Goldowitz, D et al.. Conserved and differential gene interactions in dynamical biological systems. Bioinformatics. 2011;27 (20):2851-8. doi: 10.1093/bioinformatics/btr472. PubMed PMID:21840874 PubMed Central PMC3187649.
- Rogers, TD, Dickson, PE, Heck, DH, Goldowitz, D, Mittleman, G, Blaha, CD et al.. Connecting the dots of the cerebro-cerebellar role in cognitive function: neuronal pathways for cerebellar modulation of dopamine release in the prefrontal cortex. Synapse. 2011;65 (11):1204-12. doi: 10.1002/syn.20960. PubMed PMID:21638338 PubMed Central PMC3854794.
- Reynolds, JN, Weinberg, J, Clarren, S, Beaulieu, C, Rasmussen, C, Kobor, M et al.. Fetal alcohol spectrum disorders: gene-environment interactions, predictive biomarkers, and the relationship between structural alterations in the brain and functional outcomes. Semin Pediatr Neurol. 2011;18 (1):49-55. doi: 10.1016/j.spen.2011.02.006. PubMed PMID:21575841 PubMed Central PMC4930322.
- Lewis, NJ, Goldowitz, D. NeuroDevNet: A Canada Network of Centres of Excellence--to realize a vision by effective operations and collaborative mechanisms. Semin Pediatr Neurol. 2011;18 (1):5-9. doi: 10.1016/j.spen.2011.02.008. PubMed PMID:21575834 .
- Goldowitz, D, McArthur, D. The NeuroDevNet vision. Semin Pediatr Neurol. 2011;18 (1):2-4. doi: 10.1016/j.spen.2011.02.007. PubMed PMID:21575833 .
- Shevell, M, Goldowitz, D. Inter-disciplinary research in the pediatric neurosciences: the NeuroDevNet model. Introduction. Semin Pediatr Neurol. 2011;18 (1):1. doi: 10.1016/j.spen.2011.03.001. PubMed PMID:21575832 .
- Mittleman, G, Call, SB, Cockroft, JL, Goldowitz, D, Matthews, DB, Blaha, CD et al.. Dopamine dynamics associated with, and resulting from, schedule-induced alcohol self-administration: analyses in dopamine transporter knockout mice. Alcohol. 2011;45 (4):325-39. doi: 10.1016/j.alcohol.2010.12.006. PubMed PMID:21354763 PubMed Central PMC3095708.
- Di Curzio, DL, Goldowitz, D. The genetic basis of adrenal gland weight and structure in BXD recombinant inbred mice. Mamm. Genome. 2011;22 (3-4):209-34. doi: 10.1007/s00335-011-9315-9. PubMed PMID:21347846 .
- Dickson, PE, Rogers, TD, Lester, DB, Miller, MM, Matta, SG, Chesler, EJ et al.. Genotype-dependent effects of adolescent nicotine exposure on dopamine functional dynamics in the nucleus accumbens shell in male and female mice: a potential mechanism underlying the gateway effect of nicotine. Psychopharmacology (Berl.). 2011;215 (4):631-42. doi: 10.1007/s00213-010-2159-2. PubMed PMID:21212937 .
- Lehman, AM, du Souich, C, Chai, D, Eydoux, P, Huang, JL, Fok, AK et al.. 19p13.2 microduplication causes a Sotos syndrome-like phenotype and alters gene expression. Clin. Genet. 2012;81 (1):56-63. doi: 10.1111/j.1399-0004.2010.01615.x. PubMed PMID:21204797 .
- Swanson, DJ, Goldowitz, D. Experimental Sey mouse chimeras reveal the developmental deficiencies of Pax6-null granule cells in the postnatal cerebellum. Dev. Biol. 2011;351 (1):1-12. doi: 10.1016/j.ydbio.2010.11.018. PubMed PMID:21126516 .
- Portales-Casamar, E, Swanson, DJ, Liu, L, de Leeuw, CN, Banks, KG, Ho Sui, SJ et al.. A regulatory toolbox of MiniPromoters to drive selective expression in the brain. Proc. Natl. Acad. Sci. U.S.A. 2010;107 (38):16589-94. doi: 10.1073/pnas.1009158107. PubMed PMID:20807748 PubMed Central PMC2944712.
- Swanson, DJ, Steshina, EY, Wakenight, P, Aldinger, KA, Goldowitz, D, Millen, KJ et al.. Phenotypic and genetic analysis of the cerebellar mutant tmgc26, a new ENU-induced ROR-alpha allele. Eur. J. Neurosci. 2010;32 (5):707-16. doi: 10.1111/j.1460-9568.2010.07330.x. PubMed PMID:20722722 PubMed Central PMC2974799.
- Poon, A, Li, Z, Wolfe, GW, Lu, L, Williams, RW, Hayes, NL et al.. Identification of a Chr 11 quantitative trait locus that modulates proliferation in the rostral migratory stream of the adult mouse brain. Eur. J. Neurosci. 2010;32 (4):523-37. doi: 10.1111/j.1460-9568.2010.07316.x. PubMed PMID:20718853 PubMed Central PMC3382016.
- Samaan, G, Yugo, D, Rajagopalan, S, Wall, J, Donnell, R, Goldowitz, D et al.. Foxn3 is essential for craniofacial development in mice and a putative candidate involved in human congenital craniofacial defects. Biochem. Biophys. Res. Commun. 2010;400 (1):60-5. doi: 10.1016/j.bbrc.2010.07.142. PubMed PMID:20691664 .
- Fyfe, JC, Al-Tamimi, RA, Castellani, RJ, Rosenstein, D, Goldowitz, D, Henthorn, PS et al.. Inherited neuroaxonal dystrophy in dogs causing lethal, fetal-onset motor system dysfunction and cerebellar hypoplasia. J. Comp. Neurol. 2010;518 (18):3771-84. doi: 10.1002/cne.22423. PubMed PMID:20653033 PubMed Central PMC3006439.
- Dickson, PE, Rogers, TD, Del Mar, N, Martin, LA, Heck, D, Blaha, CD et al.. Behavioral flexibility in a mouse model of developmental cerebellar Purkinje cell loss. Neurobiol Learn Mem. 2010;94 (2):220-8. doi: 10.1016/j.nlm.2010.05.010. PubMed PMID:20566377 PubMed Central PMC2922405.
- Martin, LA, Goldowitz, D, Mittleman, G. Repetitive behavior and increased activity in mice with Purkinje cell loss: a model for understanding the role of cerebellar pathology in autism. Eur. J. Neurosci. 2010;31 (3):544-55. doi: 10.1111/j.1460-9568.2009.07073.x. PubMed PMID:20105240 PubMed Central PMC2846709.
- Philip, VM, Duvvuru, S, Gomero, B, Ansah, TA, Blaha, CD, Cook, MN et al.. High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains. Genes Brain Behav. 2010;9 (2):129-59. doi: 10.1111/j.1601-183X.2009.00540.x. PubMed PMID:19958391 PubMed Central PMC2855868.
- Freedman, R, Goldowitz, D. Studies on the hippocampal formation: From basic development to clinical applications: Studies on schizophrenia. Prog. Neurobiol. 2010;90 (2):263-75. doi: 10.1016/j.pneurobio.2009.10.008. PubMed PMID:19853005 PubMed Central PMC2829353.
- Mathews, TA, Brookshire, BR, Budygin, EA, Hamre, K, Goldowitz, D, Jones, SR et al.. Ethanol-induced hyperactivity is associated with hypodopaminergia in the 22-TNJ ENU-mutated mouse. Alcohol. 2009;43 (6):421-31. doi: 10.1016/j.alcohol.2009.04.006. PubMed PMID:19801272 PubMed Central PMC2782517.
- Jiao, Y, Cai, C, Kermany, MH, Yan, J, Cai, Q, Miller, D et al.. ENU induced single mutation locus on chr 16 leads to high-frequency hearing loss in mice. Genes Genet. Syst. 2009;84 (3):219-24. . PubMed PMID:19745570 PubMed Central PMC3155952.
- Overall, RW, Kempermann, G, Peirce, J, Lu, L, Goldowitz, D, Gage, FH et al.. Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource. Front Neurosci. 2009;3 :55. doi: 10.3389/neuro.15.003.2009. PubMed PMID:20582282 PubMed Central PMC2858614.
- Jin, N, Chow, CY, Liu, L, Zolov, SN, Bronson, R, Davisson, M et al.. VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse. EMBO J. 2008;27 (24):3221-34. doi: 10.1038/emboj.2008.248. PubMed PMID:19037259 PubMed Central PMC2600653.
- Dragatsis, I, Goldowitz, D, Del Mar, N, Deng, YP, Meade, CA, Liu, L et al.. CAG repeat lengths > or =335 attenuate the phenotype in the R6/2 Huntington's disease transgenic mouse. Neurobiol. Dis. 2009;33 (3):315-30. doi: 10.1016/j.nbd.2008.10.009. PubMed PMID:19027857 PubMed Central PMC4461140.
- Yang, GS, Banks, KG, Bonaguro, RJ, Wilson, G, Dreolini, L, de Leeuw, CN et al.. Next generation tools for high-throughput promoter and expression analysis employing single-copy knock-ins at the Hprt1 locus. Genomics. 2009;93 (3):196-204. doi: 10.1016/j.ygeno.2008.09.014. PubMed PMID:18950699 .
- Crusio, WE, Goldowitz, D, Holmes, A, Wolfer, D. Standards for the publication of mouse mutant studies. Genes Brain Behav. 2009;8 (1):1-4. doi: 10.1111/j.1601-183X.2008.00438.x. PubMed PMID:18778401 .
- D'Souza, CA, Chopra, V, Varhol, R, Xie, YY, Bohacec, S, Zhao, Y et al.. Identification of a set of genes showing regionally enriched expression in the mouse brain. BMC Neurosci. 2008;9 :66. doi: 10.1186/1471-2202-9-66. PubMed PMID:18625066 PubMed Central PMC2483290.
- Matthews, DB, Morrow, AL, O'Buckley, T, Flanigan, TJ, Berry, RB, Cook, MN et al.. Acute mild footshock alters ethanol drinking and plasma corticosterone levels in C57BL/6J male mice, but not DBA/2J or A/J male mice. Alcohol. 2008;42 (6):469-76. doi: 10.1016/j.alcohol.2008.05.001. PubMed PMID:18599253 PubMed Central PMC2575102.
- Matthews, DB, Chesler, EJ, Cook, MN, Cockroft, J, Philip, VM, Goldowitz, D et al.. Genetic mapping of vocalization to a series of increasing acute footshocks using B6.A consomic and B6.D2 congenic mouse strains. Behav. Genet. 2008;38 (4):417-23. doi: 10.1007/s10519-008-9210-7. PubMed PMID:18535899 PubMed Central PMC2504763.
- Mittleman, G, Goldowitz, D, Heck, DH, Blaha, CD. Cerebellar modulation of frontal cortex dopamine efflux in mice: relevance to autism and schizophrenia. Synapse. 2008;62 (7):544-50. doi: 10.1002/syn.20525. PubMed PMID:18435424 PubMed Central PMC3854870.
- Reiner, A, Del Mar, N, Deng, YP, Meade, CA, Sun, Z, Goldowitz, D et al.. R6/2 neurons with intranuclear inclusions survive for prolonged periods in the brains of chimeric mice. J. Comp. Neurol. 2007;505 (6):603-29. doi: 10.1002/cne.21515. PubMed PMID:17948889 .
- Liu, L, Geisert, EE, Frankfurter, A, Spano, AJ, Jiang, CX, Yue, J et al.. A transgenic mouse class-III beta tubulin reporter using yellow fluorescent protein. Genesis. 2007;45 (9):560-9. doi: 10.1002/dvg.20325. PubMed PMID:17868115 PubMed Central PMC2814058.
- Hamre, KM, Goldowitz, D, Wilkinson, S, Matthews, DB. Screening for ENU-induced mutations in mice that result in aberrant ethanol-related phenotypes. Behav. Neurosci. 2007;121 (4):665-78. doi: 10.1037/0735-7044.121.4.665. PubMed PMID:17663592 .
- Cook, MN, Dunning, JP, Wiley, RG, Chesler, EJ, Johnson, DK, Miller, DR et al.. Neurobehavioral mutants identified in an ENU-mutagenesis project. Mamm. Genome. 2007;18 (8):559-72. doi: 10.1007/s00335-007-9035-3. PubMed PMID:17629744 .
- Li, S, Goldowitz, D, Swanson, DJ. The requirement of pax6 for postnatal eye development: evidence from experimental mouse chimeras. Invest. Ophthalmol. Vis. Sci. 2007;48 (7):3292-300. doi: 10.1167/iovs.06-1482. PubMed PMID:17591901 .
- Matera, I, Cockroft, JL, Moran, JL, Beier, DR, Goldowitz, D, Pavan, WJ et al.. A mouse model of Waardenburg syndrome type IV resulting from an ENU-induced mutation in endothelin 3. Pigment Cell Res. 2007;20 (3):210-5. doi: 10.1111/j.1600-0749.2007.00371.x. PubMed PMID:17516928 .
- Bao, L, Peirce, JL, Zhou, M, Li, H, Goldowitz, D, Williams, RW et al.. An integrative genomics strategy for systematic characterization of genetic loci modulating phenotypes. Hum. Mol. Genet. 2007;16 (11):1381-90. doi: 10.1093/hmg/ddm089. PubMed PMID:17428815 .
- Du, X, Jensen, P, Goldowitz, D, Hamre, KM. Wild-type cells rescue genotypically Math1-null hair cells in the inner ears of chimeric mice. Dev. Biol. 2007;305 (2):430-8. doi: 10.1016/j.ydbio.2007.02.028. PubMed PMID:17397818 .
- Thornton, JD, Swanson, DJ, Mary, MN, Pei, D, Martin, AC, Pounds, S et al.. Persistent hyperplastic primary vitreous due to somatic mosaic deletion of the arf tumor suppressor. Invest. Ophthalmol. Vis. Sci. 2007;48 (2):491-9. doi: 10.1167/iovs.06-0765. PubMed PMID:17251441 .
- Zhang, Y, Leavitt, BR, van Raamsdonk, JM, Dragatsis, I, Goldowitz, D, MacDonald, ME et al.. Huntingtin inhibits caspase-3 activation. EMBO J. 2006;25 (24):5896-906. doi: 10.1038/sj.emboj.7601445. PubMed PMID:17124493 PubMed Central PMC1698892.
- Bao, L, Zhou, M, Wu, L, Lu, L, Goldowitz, D, Williams, RW et al.. PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits. Nucleic Acids Res. 2007;35 (Database issue):D51-4. doi: 10.1093/nar/gkl797. PubMed PMID:17099235 PubMed Central PMC1669716.
- Kermany, MH, Parker, LL, Guo, YK, Miller, D, Swanson, DJ, Yoo, TJ et al.. Identification of 17 hearing impaired mouse strains in the TMGC ENU-mutagenesis screen. Hear. Res. 2006;220 (1-2):76-86. doi: 10.1016/j.heares.2006.07.011. PubMed PMID:16949226 .
- Bao, L, Wei, L, Peirce, JL, Homayouni, R, Li, H, Zhou, M et al.. Combining gene expression QTL mapping and phenotypic spectrum analysis to uncover gene regulatory relationships. Mamm. Genome. 2006;17 (6):575-83. doi: 10.1007/s00335-005-0172-2. PubMed PMID:16783639 .
- Goldowitz, D, Matthews, DB, Hamre, KM, Mittleman, G, Chesler, EJ, Becker, HC et al.. Progress in using mouse inbred strains, consomics, and mutants to identify genes related to stress, anxiety, and alcohol phenotypes. Alcohol. Clin. Exp. Res. 2006;30 (6):1066-78. doi: 10.1111/j.1530-0277.2006.00125.x. PubMed PMID:16737467 .
- Martin, LA, Goldowitz, D, Mittleman, G. Sustained attention in the mouse: a study of the relationship with the cerebellum. Behav. Neurosci. 2006;120 (2):477-81. doi: 10.1037/0735-7044.120.2.477. PubMed PMID:16719710 .
- Jablonski, MM, Wang, X, Lu, L, Miller, DR, Rinchik, EM, Williams, RW et al.. The Tennessee Mouse Genome Consortium: identification of ocular mutants. Vis. Neurosci. ;22 (5):595-604. doi: 10.1017/S0952523805225087. PubMed PMID:16332270 .
- Swanson, DJ, Tong, Y, Goldowitz, D. Disruption of cerebellar granule cell development in the Pax6 mutant, Sey mouse. Brain Res. Dev. Brain Res. 2005;160 (2):176-93. doi: 10.1016/j.devbrainres.2005.09.005. PubMed PMID:16289327 .
- Valentine, WM, Hill, KE, Austin, LM, Valentine, HL, Goldowitz, D, Burk, RF et al.. Brainstem axonal degeneration in mice with deletion of selenoprotein p. Toxicol Pathol. 2005;33 (5):570-6. doi: 10.1080/01926230500243045. PubMed PMID:16105800 .
- Jablonski, MM, Dalke, C, Wang, X, Lu, L, Manly, KF, Pretsch, W et al.. An ENU-induced mutation in Rs1h causes disruption of retinal structure and function. Mol. Vis. 2005;11 :569-81. . PubMed PMID:16088326 .
- Sun, Z, Wang, HB, Deng, YP, Lei, WL, Xie, JP, Meade, CA et al.. Increased calbindin-D28k immunoreactivity in striatal projection neurons of R6/2 Huntington's disease transgenic mice. Neurobiol. Dis. 2005;20 (3):907-17. doi: 10.1016/j.nbd.2005.05.023. PubMed PMID:15990326 .
- Goswami, J, Martin, LA, Goldowitz, D, Beitz, AJ, Feddersen, RM. Enhanced Purkinje cell survival but compromised cerebellar function in targeted anti-apoptotic protein transgenic mice. Mol. Cell. Neurosci. 2005;29 (2):202-21. doi: 10.1016/j.mcn.2005.02.010. PubMed PMID:15911345 .