Elizabeth Conibear Publications

  1. Dziurdzik, SK, Bean, BDM, Davey, M, Conibear, E. A VPS13D spastic ataxia mutation disrupts the conserved adaptor binding site in yeast Vps13. Hum. Mol. Genet. 2020; :. doi: 10.1093/hmg/ddz318. PubMed PMID:31943017 .
  2. Bean, BDM, Dziurdzik, SK, Kolehmainen, KL, Fowler, CMS, Kwong, WK, Grad, LI et al.. Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites. J. Cell Biol. 2018;217 (10):3593-3607. doi: 10.1083/jcb.201804111. PubMed PMID:30018089 PubMed Central PMC6168272.
  3. Dharwada, ST, Dalton, LE, Bean, BDM, Padmanabhan, N, Choi, C, Schluter, C et al.. The chaperone Chs7 forms a stable complex with Chs3 and promotes its activity at the cell surface. Traffic. 2018;19 (4):285-295. doi: 10.1111/tra.12553. PubMed PMID:29405545 .
  4. Lin, DTS, Davis, NG, Conibear, E. Targeting the Ras palmitoylation/depalmitoylation cycle in cancer. Biochem. Soc. Trans. 2017;45 (4):913-921. doi: 10.1042/BST20160303. PubMed PMID:28630138 .
  5. Dalton, LE, Bean, BDM, Davey, M, Conibear, E. Quantitative high-content imaging identifies novel regulators of Neo1 trafficking at endosomes. Mol. Biol. Cell. 2017;28 (11):1539-1550. doi: 10.1091/mbc.E16-11-0772. PubMed PMID:28404745 PubMed Central PMC5449152.
  6. Bean, BD, Davey, M, Conibear, E. Cargo selectivity of yeast sorting nexins. Traffic. 2017;18 (2):110-122. doi: 10.1111/tra.12459. PubMed PMID:27883263 .
  7. Lin, DT, Conibear, E. ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization. Elife. 2015;4 :e11306. doi: 10.7554/eLife.11306. PubMed PMID:26701913 PubMed Central PMC4755737.
  8. Whitfield, ST, Burston, HE, Bean, BD, Raghuram, N, Maldonado-Báez, L, Davey, M et al.. The alternate AP-1 adaptor subunit Apm2 interacts with the Mil1 regulatory protein and confers differential cargo sorting. Mol. Biol. Cell. 2016;27 (3):588-98. doi: 10.1091/mbc.E15-09-0621. PubMed PMID:26658609 PubMed Central PMC4751606.
  9. Lin, DT, Conibear, E. Enzymatic protein depalmitoylation by acyl protein thioesterases. Biochem. Soc. Trans. 2015;43 (2):193-8. doi: 10.1042/BST20140235. PubMed PMID:25849916 .
  10. Dalton, L, Davey, M, Conibear, E. Large-scale analysis of membrane transport in yeast using invertase reporters. Methods Mol. Biol. 2015;1270 :395-409. doi: 10.1007/978-1-4939-2309-0_27. PubMed PMID:25702131 .
  11. Bean, BD, Davey, M, Snider, J, Jessulat, M, Deineko, V, Tinney, M et al.. Rab5-family guanine nucleotide exchange factors bind retromer and promote its recruitment to endosomes. Mol. Biol. Cell. 2015;26 (6):1119-28. doi: 10.1091/mbc.E14-08-1281. PubMed PMID:25609093 PubMed Central PMC4357511.
  12. Stockler, S, Corvera, S, Lambright, D, Fogarty, K, Nosova, E, Leonard, D et al.. Single point mutation in Rabenosyn-5 in a female with intractable seizures and evidence of defective endocytotic trafficking. Orphanet J Rare Dis. 2014;9 :141. doi: 10.1186/s13023-014-0141-5. PubMed PMID:25233840 PubMed Central PMC4177245.
  13. Butland, SL, Sanders, SS, Schmidt, ME, Riechers, SP, Lin, DT, Martin, DD et al.. The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease. Hum. Mol. Genet. 2014;23 (15):4142-60. doi: 10.1093/hmg/ddu137. PubMed PMID:24705354 PubMed Central PMC4082372.
  14. Conibear, E, Nichols, BJ. Vesicle and organelle formation: making connections. Mol. Biol. Cell. 2013;24 (6):674. doi: 10.1091/mbc.E12-12-0875. PubMed PMID:23486398 PubMed Central PMC3596234.
  15. Babu, M, Vlasblom, J, Pu, S, Guo, X, Graham, C, Bean, BD et al.. Interaction landscape of membrane-protein complexes in Saccharomyces cerevisiae. Nature. 2012;489 (7417):585-9. doi: 10.1038/nature11354. PubMed PMID:22940862 .
  16. Vilariño-Güell, C, Wider, C, Ross, OA, Dachsel, JC, Kachergus, JM, Lincoln, SJ et al.. VPS35 mutations in Parkinson disease. Am. J. Hum. Genet. 2011;89 (1):162-7. doi: 10.1016/j.ajhg.2011.06.001. PubMed PMID:21763482 PubMed Central PMC3135796.
  17. Conibear, E. Vesicle transport: springing the TRAPP. Curr. Biol. 2011;21 (13):R506-8. doi: 10.1016/j.cub.2011.05.045. PubMed PMID:21741587 .
  18. Choi, C, Davey, M, Schluter, C, Pandher, P, Fang, Y, Foster, LJ et al.. Organization and assembly of the TRAPPII complex. Traffic. 2011;12 (6):715-25. doi: 10.1111/j.1600-0854.2011.01181.x. PubMed PMID:21453443 .
  19. Conibear, E, Davis, NG. Palmitoylation and depalmitoylation dynamics at a glance. J. Cell. Sci. 2010;123 (Pt 23):4007-10. doi: 10.1242/jcs.059287. PubMed PMID:21084560 PubMed Central PMC2987437.
  20. Conibear, E. Converging views of endocytosis in yeast and mammals. Curr. Opin. Cell Biol. 2010;22 (4):513-8. doi: 10.1016/j.ceb.2010.05.009. PubMed PMID:20538447 .
  21. Burston, HE, Maldonado-Báez, L, Davey, M, Montpetit, B, Schluter, C, Wendland, B et al.. Regulators of yeast endocytosis identified by systematic quantitative analysis. J. Cell Biol. 2009;185 (6):1097-110. doi: 10.1083/jcb.200811116. PubMed PMID:19506040 PubMed Central PMC2711619.
  22. Montpetit, B, Conibear, E. Identification of the novel TRAPP associated protein Tca17. Traffic. 2009;10 (6):713-23. doi: 10.1111/j.1600-0854.2009.00895.x. PubMed PMID:19220810 .
  23. Burston, HE, Davey, M, Conibear, E. Genome-wide analysis of membrane transport using yeast knockout arrays. Methods Mol. Biol. 2008;457 :29-39. doi: 10.1007/978-1-59745-261-8_3. PubMed PMID:19066017 .
  24. Brumm, J, Conibear, E, Wasserman, WW, Bryan, J. Discovery and expansion of gene modules by seeking isolated groups in a random graph process. PLoS ONE. 2008;3 (10):e3358. doi: 10.1371/journal.pone.0003358. PubMed PMID:18843375 PubMed Central PMC2559867.
  25. Meisler, MH, Russ, C, Montgomery, KT, Greenway, M, Ennis, S, Hardiman, O et al.. Evaluation of the Golgi trafficking protein VPS54 (wobbler) as a candidate for ALS. Amyotroph Lateral Scler. 2008;9 (3):141-8. doi: 10.1080/17482960801934403. PubMed PMID:18574757 .
  26. Weissman, Z, Shemer, R, Conibear, E, Kornitzer, D. An endocytic mechanism for haemoglobin-iron acquisition in Candida albicans. Mol. Microbiol. 2008;69 (1):201-17. doi: 10.1111/j.1365-2958.2008.06277.x. PubMed PMID:18466294 .
  27. Schluter, C, Lam, KK, Brumm, J, Wu, BW, Saunders, M, Stevens, TH et al.. Global analysis of yeast endosomal transport identifies the vps55/68 sorting complex. Mol. Biol. Cell. 2008;19 (4):1282-94. doi: 10.1091/mbc.e07-07-0659. PubMed PMID:18216282 PubMed Central PMC2291407.
  28. Kostelansky, MS, Schluter, C, Tam, YY, Lee, S, Ghirlando, R, Beach, B et al.. Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer. Cell. 2007;129 (3):485-98. doi: 10.1016/j.cell.2007.03.016. PubMed PMID:17442384 PubMed Central PMC2065850.
  29. Lam, KK, Davey, M, Sun, B, Roth, AF, Davis, NG, Conibear, E et al.. Palmitoylation by the DHHC protein Pfa4 regulates the ER exit of Chs3. J. Cell Biol. 2006;174 (1):19-25. doi: 10.1083/jcb.200602049. PubMed PMID:16818716 PubMed Central PMC2064155.
  30. Quenneville, NR, Conibear, E. Toward the systems biology of vesicle transport. Traffic. 2006;7 (7):761-8. doi: 10.1111/j.1600-0854.2006.00436.x. PubMed PMID:16787392 .
  31. Quenneville, NR, Chao, TY, McCaffery, JM, Conibear, E. Domains within the GARP subunit Vps54 confer separate functions in complex assembly and early endosome recognition. Mol. Biol. Cell. 2006;17 (4):1859-70. doi: 10.1091/mbc.e05-11-1002. PubMed PMID:16452629 PubMed Central PMC1415290.
  32. Conibear, E. An E-MAP of the ER. Cell. 2005;123 (3):366-8. doi: 10.1016/j.cell.2005.10.016. PubMed PMID:16269327 .
  33. Kweon, Y, Rothe, A, Conibear, E, Stevens, TH. Ykt6p is a multifunctional yeast R-SNARE that is required for multiple membrane transport pathways to the vacuole. Mol. Biol. Cell. 2003;14 (5):1868-81. doi: 10.1091/mbc.e02-10-0687. PubMed PMID:12802061 PubMed Central PMC165083.
  34. Conibear, E, Cleck, JN, Stevens, TH. Vps51p mediates the association of the GARP (Vps52/53/54) complex with the late Golgi t-SNARE Tlg1p. Mol. Biol. Cell. 2003;14 (4):1610-23. doi: 10.1091/mbc.e02-10-0654. PubMed PMID:12686613 PubMed Central PMC153126.
  35. Conibear, E. An ESCRT into the endosome. Mol. Cell. 2002;10 (2):215-6. doi: 10.1016/s1097-2765(02)00601-9. PubMed PMID:12191463 .
  36. Conibear, E, Stevens, TH. Studying yeast vacuoles. Meth. Enzymol. 2002;351 :408-32. doi: 10.1016/s0076-6879(02)51861-9. PubMed PMID:12073360 .
  37. Panek, HR, Conibear, E, Bryan, JD, Colvin, RT, Goshorn, CD, Robinson, LC et al.. Identification of Rgp1p, a novel Golgi recycling factor, as a protein required for efficient localization of yeast casein kinase 1 to the plasma membrane. J. Cell. Sci. 2000;113 Pt 24 :4545-55. . PubMed PMID:11082047 .
  38. Conibear, E, Stevens, TH. Vps52p, Vps53p, and Vps54p form a novel multisubunit complex required for protein sorting at the yeast late Golgi. Mol. Biol. Cell. 2000;11 (1):305-23. doi: 10.1091/mbc.11.1.305. PubMed PMID:10637310 PubMed Central PMC14776.
  39. Conibear, E, Stevens, TH. Multiple sorting pathways between the late Golgi and the vacuole in yeast. Biochim. Biophys. Acta. 1998;1404 (1-2):211-30. doi: 10.1016/s0167-4889(98)00058-5. PubMed PMID:9714809 .
  40. Conibear, E, Stevens, TH. Vacuolar biogenesis in yeast: sorting out the sorting proteins. Cell. 1995;83 (4):513-6. doi: 10.1016/0092-8674(95)90088-8. PubMed PMID:7585951 .
  41. Nothwehr, SF, Conibear, E, Stevens, TH. Golgi and vacuolar membrane proteins reach the vacuole in vps1 mutant yeast cells via the plasma membrane. J. Cell Biol. 1995;129 (1):35-46. doi: 10.1083/jcb.129.1.35. PubMed PMID:7698993 PubMed Central PMC2120360.
  42. Conibear, E, Pearse, BM. A chimera of the cytoplasmic tail of the mannose 6-phosphate/IGF-II receptor and lysozyme localizes to the TGN rather than prelysosomes where the bulk of the endogenous receptor is found. J. Cell. Sci. 1994;107 ( Pt 4) :923-32. . PubMed PMID:8056846 .
  43. Glickman, JN, Conibear, E, Pearse, BM. Specificity of binding of clathrin adaptors to signals on the mannose-6-phosphate/insulin-like growth factor II receptor. EMBO J. 1989;8 (4):1041-7. . PubMed PMID:2545438 PubMed Central PMC400912.
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