Michael Kobor Publications

  1. Gopalan, S, Carja, O, Fagny, M, Patin, E, Myrick, JW, McEwen, LM et al.. Trends in DNA Methylation with Age Replicate Across Diverse Human Populations. Genetics. 2017; :. doi: 10.1534/genetics.116.195594. PubMed PMID:28533441 .
  2. Girchenko, P, Lahti, J, Czamara, D, Knight, AK, Jones, MJ, Suarez, A et al.. Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth. Clin Epigenetics. 2017;9 :49. doi: 10.1186/s13148-017-0349-z. PubMed PMID:28503212 PubMed Central PMC5422977.
  3. Budinger, GS, Kohanski, RA, Gan, W, Kobor, MS, Amaral, LA, Armanios, M et al.. The Intersection Of Aging Biology and The Pathobiology of Lung Diseases: A Joint NHLBI/NIA Workshop. J. Gerontol. A Biol. Sci. Med. Sci. 2017; :. doi: 10.1093/gerona/glx090. PubMed PMID:28498894 .
  4. McEwen, LM, Morin, AM, Edgar, RD, MacIsaac, JL, Jones, MJ, Dow, WH et al.. Differential DNA methylation and lymphocyte proportions in a Costa Rican high longevity region. Epigenetics Chromatin. 2017;10 :21. doi: 10.1186/s13072-017-0128-2. PubMed PMID:28465725 PubMed Central PMC5408416.
  5. Lin, X, Lim, IY, Wu, Y, Teh, AL, Chen, L, Aris, IM et al.. Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome. BMC Med. 2017;15 (1):50. doi: 10.1186/s12916-017-0800-1. PubMed PMID:28264723 PubMed Central PMC5340003.
  6. Leung, JM, Fishbane, N, Jones, M, Morin, A, Xu, S, Liu, JC et al.. Longitudinal study of surrogate aging measures during human immunodeficiency virus seroconversion. Aging (Albany NY). 2017;9 (3):687-705. doi: 10.18632/aging.101184. PubMed PMID:28237978 PubMed Central PMC5391226.
  7. Lussier, AA, Weinberg, J, Kobor, MS. Epigenetics studies of fetal alcohol spectrum disorder: where are we now?. Epigenomics. 2017;9 (3):291-311. doi: 10.2217/epi-2016-0163. PubMed PMID:28234026 .
  8. Edgar, RD, Jones, MJ, Robinson, WP, Kobor, MS. An empirically driven data reduction method on the human 450K methylation array to remove tissue specific non-variable CpGs. Clin Epigenetics. 2017;9 :11. doi: 10.1186/s13148-017-0320-z. PubMed PMID:28184257 PubMed Central PMC5290610.
  9. Gref, A, Merid, SK, Gruzieva, O, Ballereau, S, Becker, A, Bellander, T et al.. Genome-Wide Interaction Analysis of Air Pollution Exposure and Childhood Asthma with Functional Follow-up. Am. J. Respir. Crit. Care Med. 2017;195 (10):1373-1383. doi: 10.1164/rccm.201605-1026OC. PubMed PMID:27901618 .
  10. Steunou, AL, Cramet, M, Rossetto, D, Aristizabal, MJ, Lacoste, N, Drouin, S et al.. Combined Action of Histone Reader Modules Regulates NuA4 Local Acetyltransferase Function but Not Its Recruitment on the Genome. Mol. Cell. Biol. 2016;36 (22):2768-2781. doi: 10.1128/MCB.00112-16. PubMed PMID:27550811 PubMed Central PMC5086519.
  11. Esposito, EA, Jones, MJ, Doom, JR, MacIsaac, JL, Gunnar, MR, Kobor, MS et al.. Differential DNA methylation in peripheral blood mononuclear cells in adolescents exposed to significant early but not later childhood adversity. Dev. Psychopathol. 2016;28 (4pt2):1385-1399. doi: 10.1017/S0954579416000055. PubMed PMID:26847422 .
  12. Horvath, S, Gurven, M, Levine, ME, Trumble, BC, Kaplan, H, Allayee, H et al.. An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease. Genome Biol. 2016;17 (1):171. doi: 10.1186/s13059-016-1030-0. PubMed PMID:27511193 PubMed Central PMC4980791.
  13. Portales-Casamar, E, Lussier, AA, Jones, MJ, MacIsaac, JL, Edgar, RD, Mah, SM et al.. DNA methylation signature of human fetal alcohol spectrum disorder. Epigenetics Chromatin. 2016;9 :25. doi: 10.1186/s13072-016-0074-4. PubMed PMID:27358653 PubMed Central PMC4926300.
  14. Clifford, RL, Jones, MJ, MacIsaac, JL, McEwen, LM, Goodman, SJ, Mostafavi, S et al.. Inhalation of diesel exhaust and allergen alters human bronchial epithelium DNA methylation. J. Allergy Clin. Immunol. 2017;139 (1):112-121. doi: 10.1016/j.jaci.2016.03.046. PubMed PMID:27321436 .
  15. Robert McMaster, W, Morrison, CJ, Kobor, MS. Epigenetics: A New Model for Intracellular Parasite-Host Cell Regulation. Trends Parasitol. 2016;32 (7):515-21. doi: 10.1016/j.pt.2016.04.002. PubMed PMID:27142564 .
  16. Aristizabal, MJ, Kobor, MS. A single flexible RNAPII-CTD integrates many different transcriptional programs. Transcription. 2016;7 (2):50-6. doi: 10.1080/21541264.2016.1163451. PubMed PMID:26985717 PubMed Central PMC4853039.
  17. Koestler, DC, Jones, MJ, Usset, J, Christensen, BC, Butler, RA, Kobor, MS et al.. Improving cell mixture deconvolution by identifying optimal DNA methylation libraries (IDOL). BMC Bioinformatics. 2016;17 :120. doi: 10.1186/s12859-016-0943-7. PubMed PMID:26956433 PubMed Central PMC4782368.
  18. De Souza, RA, Islam, SA, McEwen, LM, Mathelier, A, Hill, A, Mah, SM et al.. DNA methylation profiling in human Huntington's disease brain. Hum. Mol. Genet. 2016;25 (10):2013-2030. doi: 10.1093/hmg/ddw076. PubMed PMID:26953320 .
  19. Buschdorf, JP, Ong, ML, Ong, SX, MacIsaac, JL, Chng, K, Kobor, MS et al.. Low birth weight associates with hippocampal gene expression. Neuroscience. 2016;318 :190-205. doi: 10.1016/j.neuroscience.2016.01.013. PubMed PMID:26791528 .
  20. Teh, AL, Pan, H, Lin, X, Lim, YI, Patro, CP, Cheong, CY et al.. Comparison of Methyl-capture Sequencing vs. Infinium 450K methylation array for methylome analysis in clinical samples. Epigenetics. 2016;11 (1):36-48. doi: 10.1080/15592294.2015.1132136. PubMed PMID:26786415 PubMed Central PMC4846133.
  21. Leung, GP, Brown, JA, Glover, JN, Kobor, MS. Rtt107 BRCT domains act as a targeting module in the DNA damage response. DNA Repair (Amst.). 2016;37 :22-32. doi: 10.1016/j.dnarep.2015.10.007. PubMed PMID:26641499 .
  22. Fagny, M, Patin, E, MacIsaac, JL, Rotival, M, Flutre, T, Jones, MJ et al.. The epigenomic landscape of African rainforest hunter-gatherers and farmers. Nat Commun. 2015;6 :10047. doi: 10.1038/ncomms10047. PubMed PMID:26616214 PubMed Central PMC4674682.
  23. Oros Klein, K, Grinek, S, Bernatsky, S, Bouchard, L, Ciampi, A, Colmegna, I et al.. funtooNorm: an R package for normalization of DNA methylation data when there are multiple cell or tissue types. Bioinformatics. 2016;32 (4):593-5. doi: 10.1093/bioinformatics/btv615. PubMed PMID:26500152 PubMed Central PMC4743629.
  24. Aristizabal, MJ, Negri, GL, Kobor, MS. The RNAPII-CTD Maintains Genome Integrity through Inhibition of Retrotransposon Gene Expression and Transposition. PLoS Genet. 2015;11 (10):e1005608. doi: 10.1371/journal.pgen.1005608. PubMed PMID:26496706 PubMed Central PMC4619828.
  25. Pacis, A, Tailleux, L, Morin, AM, Lambourne, J, MacIsaac, JL, Yotova, V et al.. Bacterial infection remodels the DNA methylation landscape of human dendritic cells. Genome Res. 2015;25 (12):1801-11. doi: 10.1101/gr.192005.115. PubMed PMID:26392366 PubMed Central PMC4665002.
  26. Unternaehrer, E, O'Donnell, K, Bouvette-Turcot, AA, Gaudreau, H, Cost, K, Fleming, A et al.. Maternal early life adversities and the offspring's epigenome: A M.A.V.A.N. project. Psychoneuroendocrinology. 2015;61 :32. doi: 10.1016/j.psyneuen.2015.07.477. PubMed PMID:26383363 .
  27. de Goede, OM, Razzaghian, HR, Price, EM, Jones, MJ, Kobor, MS, Robinson, WP et al.. Nucleated red blood cells impact DNA methylation and expression analyses of cord blood hematopoietic cells. Clin Epigenetics. 2015;7 :95. doi: 10.1186/s13148-015-0129-6. PubMed PMID:26366232 PubMed Central PMC4567832.
  28. Lussier, AA, Stepien, KA, Weinberg, J, Kobor, MS. Prenatal alcohol exposure alters gene expression in the rat brain: Experimental design and bioinformatic analysis of microarray data. Data Brief. 2015;4 :239-52. doi: 10.1016/j.dib.2015.05.007. PubMed PMID:26217797 PubMed Central PMC4510447.
  29. Jones, MJ, Islam, SA, Edgar, RD, Kobor, MS. Adjusting for Cell Type Composition in DNA Methylation Data Using a Regression-Based Approach. Methods Mol. Biol. 2017;1589 :99-106. doi: 10.1007/7651_2015_262. PubMed PMID:26126446 .
  30. Beery, AK, McEwen, LM, MacIsaac, JL, Francis, DD, Kobor, MS. Natural variation in maternal care and cross-tissue patterns of oxytocin receptor gene methylation in rats. Horm Behav. 2016;77 :42-52. doi: 10.1016/j.yhbeh.2015.05.022. PubMed PMID:26122287 PubMed Central PMC4691570.
  31. Subbarao, P, Anand, SS, Becker, AB, Befus, AD, Brauer, M, Brook, JR et al.. The Canadian Healthy Infant Longitudinal Development (CHILD) Study: examining developmental origins of allergy and asthma. Thorax. 2015;70 (10):998-1000. doi: 10.1136/thoraxjnl-2015-207246. PubMed PMID:26069286 .
  32. Pan, H, Lin, X, Wu, Y, Chen, L, Teh, AL, Soh, SE et al.. HIF3A association with adiposity: the story begins before birth. Epigenomics. 2015;7 (6):937-50. doi: 10.2217/epi.15.45. PubMed PMID:26011824 PubMed Central PMC4863876.
  33. Farré, P, Jones, MJ, Meaney, MJ, Emberly, E, Turecki, G, Kobor, MS et al.. Concordant and discordant DNA methylation signatures of aging in human blood and brain. Epigenetics Chromatin. 2015;8 :19. doi: 10.1186/s13072-015-0011-y. PubMed PMID:25977707 PubMed Central PMC4430927.
  34. Jones, MJ, Goodman, SJ, Kobor, MS. DNA methylation and healthy human aging. Aging Cell. 2015;14 (6):924-32. doi: 10.1111/acel.12349. PubMed PMID:25913071 PubMed Central PMC4693469.
  35. Kaplow, IM, MacIsaac, JL, Mah, SM, McEwen, LM, Kobor, MS, Fraser, HB et al.. A pooling-based approach to mapping genetic variants associated with DNA methylation. Genome Res. 2015;25 (6):907-17. doi: 10.1101/gr.183749.114. PubMed PMID:25910490 PubMed Central PMC4448686.
  36. Gurnot, C, Martin-Subero, I, Mah, SM, Weikum, W, Goodman, SJ, Brain, U et al.. Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates. Epigenetics. 2015;10 (5):361-72. doi: 10.1080/15592294.2015.1026031. PubMed PMID:25891251 PubMed Central PMC4622680.
  37. Lussier, AA, Stepien, KA, Neumann, SM, Pavlidis, P, Kobor, MS, Weinberg, J et al.. Prenatal alcohol exposure alters steady-state and activated gene expression in the adult rat brain. Alcohol. Clin. Exp. Res. 2015;39 (2):251-61. doi: 10.1111/acer.12622. PubMed PMID:25684047 PubMed Central PMC4833439.
  38. Jiang, R, Jones, MJ, Chen, E, Neumann, SM, Fraser, HB, Miller, GE et al.. Discordance of DNA methylation variance between two accessible human tissues. Sci Rep. 2015;5 :8257. doi: 10.1038/srep08257. PubMed PMID:25660083 PubMed Central PMC4321176.
  39. Chen, L, Pan, H, Tuan, TA, Teh, AL, MacIsaac, JL, Mah, SM et al.. Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism influences the association of the methylome with maternal anxiety and neonatal brain volumes. Dev. Psychopathol. 2015;27 (1):137-50. doi: 10.1017/S0954579414001357. PubMed PMID:25640836 .
  40. Boyce, WT, Kobor, MS. Development and the epigenome: the 'synapse' of gene-environment interplay. Dev Sci. 2015;18 (1):1-23. doi: 10.1111/desc.12282. PubMed PMID:25546559 .
  41. Jiang, R, Jones, MJ, Sava, F, Kobor, MS, Carlsten, C. Short-term diesel exhaust inhalation in a controlled human crossover study is associated with changes in DNA methylation of circulating mononuclear cells in asthmatics. Part Fibre Toxicol. 2014;11 :71. doi: 10.1186/s12989-014-0071-3. PubMed PMID:25487561 PubMed Central PMC4268899.
  42. Koestler, DC, Jones, MJ, Jones, M, Kobor, MS, Kobor, M. The era of integrative genomics: more data or better methods?. Epigenomics. 2014;6 (5):463-7. doi: 10.2217/epi.14.44. PubMed PMID:25431938 PubMed Central PMC4414242.
  43. Cotton, AM, Price, EM, Jones, MJ, Balaton, BP, Kobor, MS, Brown, CJ et al.. Landscape of DNA methylation on the X chromosome reflects CpG density, functional chromatin state and X-chromosome inactivation. Hum. Mol. Genet. 2015;24 (6):1528-39. doi: 10.1093/hmg/ddu564. PubMed PMID:25381334 PubMed Central PMC4381753.
  44. Marr, AK, MacIsaac, JL, Jiang, R, Airo, AM, Kobor, MS, McMaster, WR et al.. Leishmania donovani infection causes distinct epigenetic DNA methylation changes in host macrophages. PLoS Pathog. 2014;10 (10):e1004419. doi: 10.1371/journal.ppat.1004419. PubMed PMID:25299267 PubMed Central PMC4192605.
  45. Fejes, AP, Jones, MJ, Kobor, MS. DaVIE: Database for the Visualization and Integration of Epigenetic data. Front Genet. 2014;5 :325. doi: 10.3389/fgene.2014.00325. PubMed PMID:25278960 PubMed Central PMC4166999.
  46. Miller, GE, Murphy, ML, Cashman, R, Ma, R, Ma, J, Arevalo, JM et al.. Greater inflammatory activity and blunted glucocorticoid signaling in monocytes of chronically stressed caregivers. Brain Behav. Immun. 2014;41 :191-9. doi: 10.1016/j.bbi.2014.05.016. PubMed PMID:25242587 PubMed Central PMC4973629.
  47. Goldowitz, D, Lussier, AA, Boyle, JK, Wong, K, Lattimer, SL, Dubose, C et al.. Molecular pathways underpinning ethanol-induced neurodegeneration. Front Genet. 2014;5 :203. doi: 10.3389/fgene.2014.00203. PubMed PMID:25076964 PubMed Central PMC4097813.
  48. Rossetto, D, Cramet, M, Wang, AY, Steunou, AL, Lacoste, N, Schulze, JM et al.. Eaf5/7/3 form a functionally independent NuA4 submodule linked to RNA polymerase II-coupled nucleosome recycling. EMBO J. 2014;33 (12):1397-415. doi: 10.15252/embj.201386433. PubMed PMID:24843044 PubMed Central PMC4194127.
  49. Ong, ML, Tan, PY, MacIsaac, JL, Mah, SM, Buschdorf, JP, Cheong, CY et al.. Infinium monkeys: Infinium 450K array for the Cynomolgus macaque (Macaca fascicularis). G3 (Bethesda). 2014;4 (7):1227-34. doi: 10.1534/g3.114.010967. PubMed PMID:24815017 PubMed Central PMC4455772.
  50. Chan, YA, Aristizabal, MJ, Lu, PY, Luo, Z, Hamza, A, Kobor, MS et al.. Genome-wide profiling of yeast DNA:RNA hybrid prone sites with DRIP-chip. PLoS Genet. 2014;10 (4):e1004288. doi: 10.1371/journal.pgen.1004288. PubMed PMID:24743342 PubMed Central PMC3990523.
  51. Teh, AL, Pan, H, Chen, L, Ong, ML, Dogra, S, Wong, J et al.. The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes. Genome Res. 2014;24 (7):1064-74. doi: 10.1101/gr.171439.113. PubMed PMID:24709820 PubMed Central PMC4079963.
  52. Leung, GP, Aristizabal, MJ, Krogan, NJ, Kobor, MS. Conditional genetic interactions of RTT107, SLX4, and HRQ1 reveal dynamic networks upon DNA damage in S. cerevisiae. G3 (Bethesda). 2014;4 (6):1059-69. doi: 10.1534/g3.114.011205. PubMed PMID:24700328 PubMed Central PMC4065249.
  53. Lu, PY, Kobor, MS. Maintenance of heterochromatin boundary and nucleosome composition at promoters by the Asf1 histone chaperone and SWR1-C chromatin remodeler in Saccharomyces cerevisiae. Genetics. 2014;197 (1):133-45. doi: 10.1534/genetics.114.162909. PubMed PMID:24578349 PubMed Central PMC4012474.
  54. Jones, MJ, Farré, P, McEwen, LM, Macisaac, JL, Watt, K, Neumann, SM et al.. Distinct DNA methylation patterns of cognitive impairment and trisomy 21 in Down syndrome. BMC Med Genomics. 2013;6 :58. doi: 10.1186/1755-8794-6-58. PubMed PMID:24373378 PubMed Central PMC3879645.
  55. Cotton, AM, Chen, CY, Lam, LL, Wasserman, WW, Kobor, MS, Brown, CJ et al.. Spread of X-chromosome inactivation into autosomal sequences: role for DNA elements, chromatin features and chromosomal domains. Hum. Mol. Genet. 2014;23 (5):1211-23. doi: 10.1093/hmg/ddt513. PubMed PMID:24158853 PubMed Central PMC4051349.
  56. Chang, J, Zhou, Y, Hu, X, Lam, L, Henry, C, Green, EM et al.. The molecular mechanism of a cis-regulatory adaptation in yeast. PLoS Genet. 2013;9 (9):e1003813. doi: 10.1371/journal.pgen.1003813. PubMed PMID:24068973 PubMed Central PMC3778017.
  57. Powell, ND, Sloan, EK, Bailey, MT, Arevalo, JM, Miller, GE, Chen, E et al.. Social stress up-regulates inflammatory gene expression in the leukocyte transcriptome via β-adrenergic induction of myelopoiesis. Proc. Natl. Acad. Sci. U.S.A. 2013;110 (41):16574-9. doi: 10.1073/pnas.1310655110. PubMed PMID:24062448 PubMed Central PMC3799381.
  58. Aristizabal, MJ, Negri, GL, Benschop, JJ, Holstege, FC, Krogan, NJ, Kobor, MS et al.. High-throughput genetic and gene expression analysis of the RNAPII-CTD reveals unexpected connections to SRB10/CDK8. PLoS Genet. 2013;9 (8):e1003758. doi: 10.1371/journal.pgen.1003758. PubMed PMID:24009531 PubMed Central PMC3757075.
  59. Jones, MJ, Fejes, AP, Kobor, MS. DNA methylation, genotype and gene expression: who is driving and who is along for the ride?. Genome Biol. 2013;14 (7):126. doi: 10.1186/gb-2013-14-7-126. PubMed PMID:23899167 PubMed Central PMC4054606.
  60. Lam, LL, Emberly, E, Fraser, HB, Neumann, SM, Chen, E, Miller, GE et al.. Reply to Suderman et al.: Importance of accounting for blood cell composition in epigenetic studies. Proc. Natl. Acad. Sci. U.S.A. 2013;110 (14):E1247. . PubMed PMID:23667927 PubMed Central PMC3619326.
  61. Price, ME, Cotton, AM, Lam, LL, Farré, P, Emberly, E, Brown, CJ et al.. Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array. Epigenetics Chromatin. 2013;6 (1):4. doi: 10.1186/1756-8935-6-4. PubMed PMID:23452981 PubMed Central PMC3740789.
  62. Maltby, VE, Martin, BJ, Brind'Amour, J, Chruscicki, AT, McBurney, KL, Schulze, JM et al.. Histone H3K4 demethylation is negatively regulated by histone H3 acetylation in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U.S.A. 2012;109 (45):18505-10. doi: 10.1073/pnas.1202070109. PubMed PMID:23091032 PubMed Central PMC3494965.
  63. Lam, LL, Emberly, E, Fraser, HB, Neumann, SM, Chen, E, Miller, GE et al.. Factors underlying variable DNA methylation in a human community cohort. Proc. Natl. Acad. Sci. U.S.A. 2012;109 Suppl 2 :17253-60. doi: 10.1073/pnas.1121249109. PubMed PMID:23045638 PubMed Central PMC3477380.
  64. Stefanowicz, D, Hackett, TL, Garmaroudi, FS, Günther, OP, Neumann, S, Sutanto, EN et al.. DNA methylation profiles of airway epithelial cells and PBMCs from healthy, atopic and asthmatic children. PLoS ONE. 2012;7 (9):e44213. doi: 10.1371/journal.pone.0044213. PubMed PMID:22970180 PubMed Central PMC3435400.
  65. Wei, W, Coelho, CM, Li, X, Marek, R, Yan, S, Anderson, S et al.. p300/CBP-associated factor selectively regulates the extinction of conditioned fear. J. Neurosci. 2012;32 (35):11930-41. doi: 10.1523/JNEUROSCI.0178-12.2012. PubMed PMID:22933779 PubMed Central PMC3466419.
  66. Maltby, VE, Martin, BJ, Schulze, JM, Johnson, I, Hentrich, T, Sharma, A et al.. Histone H3 lysine 36 methylation targets the Isw1b remodeling complex to chromatin. Mol. Cell. Biol. 2012;32 (17):3479-85. doi: 10.1128/MCB.00389-12. PubMed PMID:22751925 PubMed Central PMC3422011.
  67. Price, EM, Cotton, AM, Peñaherrera, MS, McFadden, DE, Kobor, MS, Robinson, W et al.. Different measures of "genome-wide" DNA methylation exhibit unique properties in placental and somatic tissues. Epigenetics. 2012;7 (6):652-63. doi: 10.4161/epi.20221. PubMed PMID:22531475 PubMed Central PMC3398992.
  68. Fraser, HB, Lam, LL, Neumann, SM, Kobor, MS. Population-specificity of human DNA methylation. Genome Biol. 2012;13 (2):R8. doi: 10.1186/gb-2012-13-2-r8. PubMed PMID:22322129 PubMed Central PMC3334571.
  69. Stirling, PC, Chan, YA, Minaker, SW, Aristizabal, MJ, Barrett, I, Sipahimalani, P et al.. R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants. Genes Dev. 2012;26 (2):163-75. doi: 10.1101/gad.179721.111. PubMed PMID:22279048 PubMed Central PMC3273840.
  70. Hentrich, T, Schulze, JM, Emberly, E, Kobor, MS. CHROMATRA: a Galaxy tool for visualizing genome-wide chromatin signatures. Bioinformatics. 2012;28 (5):717-8. doi: 10.1093/bioinformatics/bts007. PubMed PMID:22238257 .
  71. Schulze, JM, Hentrich, T, Nakanishi, S, Gupta, A, Emberly, E, Shilatifard, A et al.. Splitting the task: Ubp8 and Ubp10 deubiquitinate different cellular pools of H2BK123. Genes Dev. 2011;25 (21):2242-7. doi: 10.1101/gad.177220.111. PubMed PMID:22056669 PubMed Central PMC3219228.
  72. Essex, MJ, Boyce, WT, Hertzman, C, Lam, LL, Armstrong, JM, Neumann, SM et al.. Epigenetic vestiges of early developmental adversity: childhood stress exposure and DNA methylation in adolescence. Child Dev. ;84 (1):58-75. doi: 10.1111/j.1467-8624.2011.01641.x. PubMed PMID:21883162 PubMed Central PMC3235257.
  73. Lin, Q, Wei, W, Coelho, CM, Li, X, Baker-Andresen, D, Dudley, K et al.. The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory. Nat. Neurosci. 2011;14 (9):1115-7. doi: 10.1038/nn.2891. PubMed PMID:21841775 .
  74. Wang, AY, Aristizabal, MJ, Ryan, C, Krogan, NJ, Kobor, MS. Key functional regions in the histone variant H2A.Z C-terminal docking domain. Mol. Cell. Biol. 2011;31 (18):3871-84. doi: 10.1128/MCB.05182-11. PubMed PMID:21791612 PubMed Central PMC3165728.
  75. Leung, GP, Lee, L, Schmidt, TI, Shirahige, K, Kobor, MS. Rtt107 is required for recruitment of the SMC5/6 complex to DNA double strand breaks. J. Biol. Chem. 2011;286 (29):26250-7. doi: 10.1074/jbc.M111.235200. PubMed PMID:21642432 PubMed Central PMC3138301.
  76. Cotton, AM, Lam, L, Affleck, JG, Wilson, IM, Peñaherrera, MS, McFadden, DE et al.. Chromosome-wide DNA methylation analysis predicts human tissue-specific X inactivation. Hum. Genet. 2011;130 (2):187-201. doi: 10.1007/s00439-011-1007-8. PubMed PMID:21597963 PubMed Central PMC3132437.
  77. Lenstra, TL, Benschop, JJ, Kim, T, Schulze, JM, Brabers, NA, Margaritis, T et al.. The specificity and topology of chromatin interaction pathways in yeast. Mol. Cell. 2011;42 (4):536-49. doi: 10.1016/j.molcel.2011.03.026. PubMed PMID:21596317 PubMed Central PMC4435841.
  78. Reynolds, JN, Weinberg, J, Clarren, S, Beaulieu, C, Rasmussen, C, Kobor, M et al.. Fetal alcohol spectrum disorders: gene-environment interactions, predictive biomarkers, and the relationship between structural alterations in the brain and functional outcomes. Semin Pediatr Neurol. 2011;18 (1):49-55. doi: 10.1016/j.spen.2011.02.006. PubMed PMID:21575841 PubMed Central PMC4930322.
  79. Yuen, RK, Neumann, SM, Fok, AK, Peñaherrera, MS, McFadden, DE, Robinson, WP et al.. Extensive epigenetic reprogramming in human somatic tissues between fetus and adult. Epigenetics Chromatin. 2011;4 :7. doi: 10.1186/1756-8935-4-7. PubMed PMID:21545704 PubMed Central PMC3112062.
  80. Takahashi, YH, Schulze, JM, Jackson, J, Hentrich, T, Seidel, C, Jaspersen, SL et al.. Dot1 and histone H3K79 methylation in natural telomeric and HM silencing. Mol. Cell. 2011;42 (1):118-26. doi: 10.1016/j.molcel.2011.03.006. PubMed PMID:21474073 PubMed Central PMC3085244.
  81. Dudley, KJ, Li, X, Kobor, MS, Kippin, TE, Bredy, TW. Epigenetic mechanisms mediating vulnerability and resilience to psychiatric disorders. Neurosci Biobehav Rev. 2011;35 (7):1544-51. doi: 10.1016/j.neubiorev.2010.12.016. PubMed PMID:21251925 .
  82. Lehman, AM, du Souich, C, Chai, D, Eydoux, P, Huang, JL, Fok, AK et al.. 19p13.2 microduplication causes a Sotos syndrome-like phenotype and alters gene expression. Clin. Genet. 2012;81 (1):56-63. doi: 10.1111/j.1399-0004.2010.01615.x. PubMed PMID:21204797 .
  83. Kobor, MS, Weinberg, J. Focus on: epigenetics and fetal alcohol spectrum disorders. Alcohol Res Health. 2011;34 (1):29-37. . PubMed PMID:23580038 PubMed Central PMC3860549.
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