Potential Breakthrough for Huntington’s Disease

Lancet, Neurology paper released “Neurofilament light protein in blood as a potential biomarker of neurodegeneration in Huntington’s disease: a retrospective cohort analysis”.

Authors: Lauren M Byrne, MRes, Filipe B Rodrigues, MD, Prof Kaj Blennow, PhD,  Prof Alexandra Durr, PhD, Prof Blair R Leavitt, PhD, Prof Raymund A C Roos, PhD, Rachael I Scahill, PhD, Prof Sarah J Tabrizi, PhD, Prof Henrik Zetterberg, PhD, Prof Douglas Langbehn, PhD, Dr Edward J Wild, PhD.


Blood biomarkers of neuronal damage could facilitate clinical management of and therapeutic development for Huntington’s disease. We investigated whether neurofilament light protein NfL (also known as NF-L) in blood is a potential prognostic marker of neurodegeneration in patients with Huntington’s disease.

Read more: http://www.thelancet.com/journals/laneur/article/PIIS1474-4422(17)30124-2/fulltext

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