OVERVIEW
Research laboratories at CMMT are equipped with state-of-the-art technology that is actively upgraded to meet the evolving demands of world-class research. Core Facilities that are shared amongst our researchers are an essential part of maintaining this high standard of excellence. These facilities provide our researchers immediate and cost-effective access to essential research services including animal model facilities, high-throughput genetic analysis, scientific supplies procurement, and IT systems infrastructure management.
With collaboration and sharing at the heart of CMMT’s research culture, the services of these facilities are also offered to and actively utilized by researchers in the wider research community. CMMT’s unique combination of facilities, resources, and staff create a supportive and collaborative research environment that is key to the success of our research programs.
OUR SERVICES
Bioanalyzer Services
We provide researchers access to the state-of-the-art microfluidics-based functionality of the Agilent 2100 bioanalyzer system from Agilent Technologies.
DNA Purification
We understand the importance of having the highest quality genomic DNA for effective genotyping. We use an organic-free, modified salt precipitation method for purifying DNA. The use of toxic organic reagents is completely avoided.
DNA Sequencing
We offer access to automated DNA sequencing and DNA fragment analysis services on an ABI 3130xl 16-capillary genetic analyzer, with results typically available in one to two business days.
Gene Expression Profiling
CMMT's gene expression profiling services uses Illumina technology to deliver the latest high-performance arrays. Illumina arrays interrogate multiple whole genomes or focused sets of target genes across large sample populations with very low cost per sample.
Genotyping Services
The CMMT Genotyping Core Facility provides high-throughput genotyping, and DNA purification services to researchers in the academic, industrial, and pharmaceutical communities.
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MAPS
Our Mouse Animal Production Service (MAPS) is set up to perform Embryonic Stem cell microinjections to generate chimeras for researchers from any institution. Related services include providing untargeted ES cell lines to researchers, generating Mouse Embryonic Fibroblasts (MEFs), and other cell culture related projects. In addition, we perform in vitro fertilization (IVF) and other strain recovery services, as well cryopreserve in-house strains, for CMMT and CFRI researchers. Finally, we are delighted to discuss custom work.
Cryopreservation Services
The CMMT MAPS (Mouse Animal Production Service) offers strain cryopreservation services to researchers currently maintaining mouse colonies within the barrier facility.
ES Cell Injection
Our MAPS team is ready to inject targeted ES cells into blastocysts to produce chimeric mice for your project. Untargeted ES cells can be provided to the researcher.
Scientific Store
To meet the need for immediate access to common lab reagents, CMMT operates an on-site stockroom that carries common consumables from vendors such as ThermoFisher, VWR Scientific, Diamed Scientific, and Rainin, as well as a wide selection of reagents on consignment from Invitrogen, Qiagen, Promega, Pierce, Hyclone, and BioRad Laboratories.
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