Ekaterina Nosova PhD Postdoctoral Research Fellow Group Wasserman Lab Email Direct line Fax +1 (604) 875-3819

ADDITIONAL CONTACT INFORMATION

EDUCATION

• Doctorate (PhD), Universuta degli studi di Salerno, Italy (03/2011)
• Diploma, Specialist degree, Saint Petersburg State University, Russia (06/2007)

RESEARCH INTERESTS

Algorithms and Complexity; Computational Biology; Computer Systems Software; Gene Regulation Analysis; Mathematical Modelling; Mathematics of Computing; Numerical Analysis; Optimization; Statistical Genomics; Transcription Factors

COLLABORATORS

• Wyeth W. Wasserman, Ph.D. Senior Scientist and Associate Director, Centre for Molecular Medicine and Therapeutics Scientist Level 3, Child and Family Research Institute Professor, Department of Medical Genetics, University of British Columbia
• Jennifer Bryan, Associate Professor, Department of Statistics & Michael Smith Laboratories, University of British Columbia
• prof. Roberto Tagliaferri, robtag@unisa.it, Dept. of Mathematics and Informatics, University of Salerno 84084 Fisciano, ITALY
• prof. Giancarlo Raiconi, gianni@unisa.it, Dept. of Mathematics and Informatics, University of Salerno 84084 Fisciano, ITALY
• prof. Rino Miele, miele@na.infn.it, Dipartimento di Scienze Fisiche, Università degli Studi di Napoli \"Federico I\", Napoli, ITALY
• prof. Francesco Masulli, masulli@disi.unige.it, DISI, Dept. Computer and Information Sciences, University of Genova, 16146, Genova, ITALY

PROFESSIONAL ACTIVITIES

Two last years of my PhD work I deal with unsupervised classification of the large data matrices with respect to rows and columns together (Biclustering). With following application to biological and genetics data, proposed by, for example, Microarray technology. For this problem many mathematical techniques have been used. In my work I apply such mathematical fields as: Clustering techniques (K-means and Hierarchical Clustering), different methods of the Preprocessing of the data sets (one of them PCA analysis), Statistics, Biclustering, different data Validations (Enrichment, p-value and other methods), the problems of Optimization, Global and Local minimums finding (including GA algorithms), Obtaining of the objective functions, Numerical methods, Fuzzy logic, Genetics and Probabilistic approaches. In the first year of my PhD I studied application of wavelets to some mathematical problems. As additional studies I work with Neural Networks, and their application to Auto-encoders, mathematical basis of NN and their different types. I have an interest in complex-value Neural Networks. In the present moment I am working on SOBA software that permits to make statistical analyse of the genetic data.

AWARDS & HONORS

Fellowship of Francesco Severi, Istituto Nazionale di Alta Matematica F.Severi, Italy, Effective: 02/2008, Ending: 02/2011, PhD

PRESENTATIONS

• “Toward an Improved Combinatoric Algorithm”, Network Tools and Applications in Biology Workshop(November 29 - December 1, 2010, Naples, Italy (NETTAB 2010))
• “Biclustering by Resampling”, Seventh International Meeting on computational intelligence methods for bioinformatics and biostatistics (Palermo September 16-18 2010 (CIBB10))
• "A Combinatoric biclustering algorithm", WIRN 2010 workshop (Vietri sul Mare 28/05/2010)

Publications